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Cyclic amide
A lactam is a cyclic amide, formally derived from an amino carboxylic acid through cyclization reactions. The term is a portmanteau of the words lactone
Lactam
Class of broad-spectrum antibiotics
β-Lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a β-lactam ring in their chemical structure. This includes penicillin derivatives
Β-Lactam_antibiotic
Family of chemical compounds
A β-lactam (beta-lactam) ring is a four-membered lactam. A lactam is a cyclic amide, and beta-lactams are named so because the nitrogen atom is attached
Β-Lactam
Group of antibiotics derived from fungi
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from Penicillium moulds, principally P. chrysogenum and P. rubens.
Penicillin
Class of pharmaceutical drugs
The cephalosporins (sg. /ˌsɛfələˈspɔːrɪn, ˌkɛ-, -loʊ-/) are a class of β-lactam antibiotics originally derived from the fungal genus Acremonium, which was
Cephalosporin
Class of enzymes
a four-atom ring known as a beta-lactam (β-lactam) ring. Through hydrolysis, the enzyme lactamase breaks the β-lactam ring open, deactivating the molecule's
Beta-lactamase
Beta-lactam antibiotic
bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a β-lactam antibiotic within the class of first-generation cephalosporins. It works
Cefalexin
Chemical compound
Vince lactam is the commercial name given to the bicyclic molecule γ-lactam 2-azabicyclo[2.2.1]hept-5-en-3-one. This lactam is a versatile chemical intermediate
Vince_lactam
Broad-spectrum antibiotic
allergic reactions including anaphylaxis. Those who are allergic to other β-lactam antibiotics are more likely to be allergic to meropenem as well. Use in
Meropenem
Drugs that inhibit β-Lactamase enzymes
degradation of β-lactam (beta-lactam) antibiotics. Beta-lactamases are a family of enzymes which create bacterial resistance to beta-lactam antibiotics by
Β-Lactamase_inhibitor
Class of proteins
the way by which the protein was discovered. All β-lactam antibiotics (except for tabtoxinine-β-lactam, which inhibits glutamine synthetase) bind to PBPs
Penicillin-binding_proteins
Chemical compound
butyrolactam, is an organic compound consisting of a 5-membered lactam, making it the simplest γ-lactam. It is a colorless liquid that is miscible with water and
2-Pyrrolidone
Chemical compound
ruthenium complexes, The compound, a colorless solid, is classified as a lactam. It is the monomer of nylon 5, a polyamide: n (CH2)4CONH → [HN(CH2)4CO)]n
2-Piperidinone
Molecule used to overcome antibiotic resistance in bacteria
Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined
Clavulanic_acid
Beta-lactam antibiotic
and breastfeeding does not appear to be harmful. Amoxicillin is in the β-lactam family of antibiotics. Amoxicillin was discovered in 1958 and came into
Amoxicillin
Bacterium responsible for difficult-to-treat infections in humans
group of Staphylococcus aureus strains that are resistant to β-lactam antibiotics. The β-lactam group is a broad-spectrum group of antibiotics that includes
Methicillin-resistant Staphylococcus aureus
Methicillin-resistant_Staphylococcus_aureus
Antibiotic medication
Methicillin (USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class. Methicillin was discovered in 1960.
Methicillin
Antibiotic medication
Piperacillin is a broad-spectrum β-lactam antibiotic of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins
Piperacillin
This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed
List_of_β-lactam_antibiotics
Bactericidal antibiotics
antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with other β-lactam antibiotics (e.g. penicillins
Discovery and development of cephalosporins
Discovery_and_development_of_cephalosporins
Monocyclic β-lactam antibiotics
bacterially-produced monocyclic β-lactam antibiotics. The β-lactam ring is not fused to another ring, in contrast to most other β-lactams. Monobactams are narrow-spectrum
Monobactam
Antibiotic derived from Penicillin
Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible (non-resistant) Gram-positive
Dicloxacillin
Chemical compound
The Ojima lactam, (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone, is an organic compound of some importance in the commercial production
Ojima_lactam
Chemical compound
organic compound with the formula (CH2)5C(O)NH. This colourless solid is a lactam (a cyclic amide) of caproic acid. Global demand for this compound is approximately
Caprolactam
Antibiotic combination drug
the treatment of urinary tract infections. It contains cefoperazone, a β-lactam antibiotic, and sulbactam, a β-lactamase inhibitor, which helps prevent
Cefoperazone/sulbactam
Chemical compound
Tabtoxinine β-lactam is a monobactam antibiotic derived from tabtoxin. Unlike other β-lactam antibiotics, which covalently inhibit penicillin-binding proteins
Tabtoxinine_β-lactam
Gene for resistance to beta-lactam antibiotics
helps form the bacterial cell wall. PBP2A has a lower affinity for beta-lactam antibiotics such as methicillin and penicillin than DD-transpeptidase does
MecA
Class of highly effective antibiotic agents
to penicillins and cephalosporins, carbapenems are members of the beta-lactam antibiotics drug class, which kill bacteria by binding to penicillin-binding
Carbapenem
Antibiotic resistance caused by a plasmid
resistance to most of the antibiotic classes used nowadays, for example, beta-lactams, fluoroquinolones and aminoglycosides. It is very common for the resistance
Plasmid-mediated_resistance
Chemical compound
allergic reactions including anaphylaxis. Those who are allergic to other β-lactam have a low rate of allergy to aztreonam. Use in pregnancy appears to be
Aztreonam
American record label
Beta-lactam Ring Records is an American independent record label founded by Chris McBeth in 2000. The label relocated from its founding city of Austin
Beta-lactam_Ring_Records
Antibiotic medication
Because it is a penicillin, it also falls within the larger class of β-lactam antibiotics. Its main clinical use is as an injectable antibiotic for the
Ticarcillin
Argentine musician (born 1972)
Digital Narcis, Drone Records,[citation needed] Locust, Sedimental, Beta-Lactam Ring Records, Celebrate Psi Phenomenon, RRR, Audiobot Records, Roaratorio
Anla_Courtis
Form of chemical synthesis
2+2 cycloaddition to produce a β-lactam 3. The reaction carries particular importance in the synthesis of β-lactam antibiotics. The Staudinger synthesis
Staudinger_synthesis
Antibiotic derived from Penicillin
used in those who are allergic to penicillin. It is a narrow-spectrum beta-lactam antibiotic of the penicillin class. It is similar in effect to cloxacillin
Flucloxacillin
Group of antibiotics
benzylpenicillin, hence the name). Like other penicillins and beta-lactam antibiotics, they contain a beta-lactam ring that is crucial to its antibacterial activity.[citation
Aminopenicillin
Combination antibiotic medication
allergic reactions including anaphylaxis. Those who are allergic to other β-lactam are more likely to be allergic to piperacillin/tazobactam. Use in pregnancy
Piperacillin/tazobactam
Species of Gram-positive bacterium
that cleaves the β-lactam ring of the penicillin molecule, rendering the antibiotic ineffective. Penicillinase-resistant β-lactam antibiotics, such as
Staphylococcus_aureus
Combination antibiotic medication
co-ticarclav, is a combination antibiotic consisting of ticarcillin, a β-lactam antibiotic, and clavulanic acid, a β-lactamase inhibitor. This combination
Ticarcillin/clavulanic_acid
Group of β-lactam antibiotics
Cephamycins are a group of β-lactam antibiotics. They are very similar to cephalosporins, and the cephamycins are sometimes classified as cephalosporins
Cephamycin
Japanese band
Crying "Look", 2004, Beta-Lactam Ring City Calls Revolution, 2005, Beta-Lactam Ring Pirate Radio (digital only), 2006, Beta-Lactam Ring Kuruurew vs. Gmfpto
Green Milk from the Planet Orange
Green_Milk_from_the_Planet_Orange
Antibiotic medication
color to amber or reddish suggests hydrolysis of the amide bond of the β-lactam ring, thereby affecting the antimicrobial activity of the antibiotic. Diluents
Ceftriaxone
Antibiotic medication
allergy. Use during pregnancy is generally safe in the penicillin and β-lactam class of medications. Benzylpenicillin is on the World Health Organization's
Benzylpenicillin
Chemical compound
N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam. It is a colorless liquid, although impure samples can appear yellow. It
N-Methyl-2-pyrrolidone
Pathogen resistance to medications
responsible for breaking down beta-lactams). Beta-lactam bacterial resistance can also be dealt with by administering beta-lactam antibiotics with drugs that
Drug_resistance
Medication for urinary tract infections
used beta-lactam antibiotics for UTIs include cephalosporins and penicillin. By binding to penicillin-binding proteins through their beta-lactam rings, beta-lactam
Urinary_anti-infective_agent
Combination drug
and sold under the tradename Magnapen, is a combination drug of the two β-lactam antibiotics, ampicillin and flucloxacillin, both in equal amounts, available
Ampicillin/flucloxacillin
Treatment-resistant bacterium
second general mechanism for beta-lactam resistance. PBPs, also known as transpeptidases, are targets for beta-lactams. These enzymes (PBPs) are involved
Antibiotic resistance in gonorrhea
Antibiotic_resistance_in_gonorrhea
Small motifs in proteins and polypeptides
compound called Lactam. There are a couple types of amide rings (lactams) and are classified by the size of the ring.[citation needed] β-lactam which is a
Amide_ring
Chemical compound
subclass of the broader β-lactam family of antibiotics and related compounds. They are bicyclic ring systems containing a β-lactam moiety fused with a five-member
Penam
Class of enzymes
enzymology, a 2-aminohexano-6-lactam racemase (EC 5.1.1.15) is an enzyme that catalyzes the chemical reaction L-2-aminohexano-6-lactam ⇌ {\displaystyle \rightleftharpoons
2-aminohexano-6-lactam racemase
2-aminohexano-6-lactam_racemase
Antibiotic derived from Penicillin
Oxacillin (trade name Bactocill) is a narrow-spectrum second-generation beta-lactam antibiotic of the penicillin class developed by Beecham. It was patented
Oxacillin
Chemical compound
name Poly(dodecano-12-lactam) Other names Polyamide 12, PA 12, polylaurolactam, Polylaurinlactam, poly(12-aminododecanoic acid lactam); Daiamid (Daicel Chemical
Nylon_12
Combination antibiotic drug
infections, and hospital-acquired pneumonia. It contains meropenem, a beta-lactam antibiotic; and vaborbactam, a beta-lactamase inhibitor. It is given by
Meropenem/vaborbactam
Chemical compound
carbonyl carbon and the nitrogen in the beta-lactam ring of susceptible beta-lactams and members of beta-lactam subclasses (including certain cephalosporins)
Nitrocefin
Antibiotic medication
reactions (such as anaphylaxis or severe skin reactions) to other beta-lactam antibiotics in the past. Common side effects are diarrhoea (in 5% of people
Ertapenem
Multi-component named reaction in organic chemistry
carboxylic acids and used the Ugi reaction to create lactams of various sizes. Short et al. have prepared γ-lactams from keto-acids on solid-support. The Ugi reaction
Ugi_reaction
Chemical compound
Enterobacteriaceae. This unique profile allows nacubactam to both protect partner β-lactam antibiotics from degradation and exert direct antibacterial effects. As
Nacubactam
Inflammation of abdominal organ lining
Gram-positive bacteria, Gram-negative bacteria, and anaerobic bacteria. Beta-lactams with beta-lactamase inhibitors can also be used; examples include ampicillin/sulbactam
Peritonitis
Species of bacterium
multiple antibiotics, including oxazolidinones, quinolones, and most β-lactams, such as cephalosporins. E. faecalis has been frequently found in reinfected
Enterococcus_faecalis
Chemical compound
Dalpiciclib is a drug for the treatment of various forms of cancer. In China, dalpiciclib is approved for use in combination with fulvestrant for treatment
Dalpiciclib
Veterinary medical products classification subgroup
ATCvet code QJ51 Antibacterials for intramammary use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System for veterinary
ATCvet_code_QJ51
Chemical compound
first-generation semisynthetic derivative of antibiotic cephalosporin C. It is a Beta lactam antibiotic, like penicillin. Its chemical structure contains cephems,carboxyl
Cephaloridine
Fourth-generation Cephalosporin Antibiotic
mortality was increased in people treated with cefepime compared with other β-lactam antibiotics. In response, the U.S. Food and Drug Administration (FDA) performed
Cefepime
Antibiotic resistant bacteria
gentamicin, rifampin, linezolid, trimethoprim/sulfamethoxazole, or a beta-lactam antibiotic). Three classes of vancomycin-resistant S. aureus have emerged
Vancomycin-resistant Staphylococcus aureus
Vancomycin-resistant_Staphylococcus_aureus
Chemical compound
Cefotaxime is a β-lactam antibiotic (which refers to the structural components of the drug molecule itself). As a class, β-lactams inhibit bacterial cell
Cefotaxime
Benzodiazepine
Mexazolam (marketed under the trade names Melex and Sedoxil) is a drug which is a benzodiazepine derivative. Mexazolam has been trialed for anxiety and
Mexazolam
Musical artist (born 1969)
(Beta-lactam Ring Records, 2006) Black Beauty (Beta-lactam Ring Records, 2007) Black End (Beta-lactam Ring Records, 2007) Black Hole (Beta-lactam Ring
Andrew_Liles
Antibiotic resistance enzyme in bacteria
some strains of bacteria that confers resistance to a broad range of beta-lactam antibiotics. These include the antibiotics of the carbapenem family, which
New Delhi metallo-beta-lactamase 1
New_Delhi_metallo-beta-lactamase_1
Chemical compound
Baxdrostat, sold under the brand name Baxfendy, is a medication used for the treatment of hypertension (high blood pressure). It is an aldosterone synthase
Baxdrostat
Chemical compound
antibiotic “cousins” the penicillins. Like penicillins, carbapenems contain a β-lactam ring (cyclic amide) fused to a five-membered ring. Carbapenems differ in
Thienamycin
Antibiotic-resistant bacteria
nursing homes. Independent risk factors for CRE infection include use of beta-lactam antibiotics and the use of mechanical ventilation. Patients with diabetes
Carbapenem-resistant enterobacteriaceae
Carbapenem-resistant_enterobacteriaceae
Life-threatening response to infection
severe sepsis and septic shock, broad-spectrum antibiotics (usually two, a β-lactam antibiotic with broad coverage, or broad-spectrum carbapenem combined with
Sepsis
Organic compound
melting urea with glycine. Uric acid displays lactam–lactim tautomerism. Uric acid crystallizes in the lactam form, with computational chemistry also indicating
Uric_acid
Chemical compound
Tebipenem pivoxil, sold under the brand name Orapenem among others, is a beta-lactam antibiotic medication used for the treatment of complicated urinary tract
Tebipenem_pivoxil
Chemical compound
which are obtained from the penicillins by the hydrolytic opening of the lactam ring (as by the action of a beta-lactamase). Hypersensitivity is the most
Penicilloic_acid
Herbicide
Flumioxazin is a synthetic herbicide used for control of broadleaf weeds in agricultural areas. Valent U.S.A. Corporation, a division of Sumitomo Chemical
Flumioxazin
Genus of bacteria
peptidoglycan makes them naturally resistant to antibiotics such as the beta-lactam antibiotics that target cell wall synthesis. They can be parasitic or saprotrophic
Mycoplasma
Benzodiazepine medication
Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, bipolar
Clonazepam
Genus of bacteria
spp. are usually susceptible to antibiotics, but the emergence of beta-lactam-resistant strains has been observed as early as 1980. Genes for antibiotic
Capnocytophaga
Species of bacterium
an extracellular delivery system of beta-lactam resistance that promotes the survival of otherwise beta-lactam sensitive bacteria in the vicinity of M
Moraxella_catarrhalis
Combination antibiotic medication
bacterial infections. It is a combination consisting of amoxicillin, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor. It is specifically
Amoxicillin/clavulanic_acid
Chemical compound
Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction. It is a PDE5 inhibitor. It
Vardenafil
Pharmaceutical compound
β-CCB β-CCE β-CCM β-CCP β-EMGBL Anabolic steroids Amiloride Anisatin β-Lactams (e.g., penicillins, cephalosporins, carbapenems) Basmisanil Bemegride Bicyclic
Imidazoleacetic_acid
Chemical compound
Deruxtecan is a chemical compound and a derivative of exatecan that acts as topoisomerase I inhibitor. It is available linked to specific monoclonal antibody
Deruxtecan
Chemical compound
that exists as tautomers. The second tautomer is 2-hydroxypyridine. This lactam lactim tautomerism can also be exhibited in many related compounds. The
2-Pyridone
NMDA receptor antagonist acting at the glycine site
L-701324 is an antagonist of the NMDA receptor. It appears to have activity in animal models of depression. L-701324 appears to be an antagonist of the
L-701324
Bacteria that give a positive result in the Gram stain test
absence of the outer membrane. For example, penicillin contains a beta-lactam ring that binds to enzymes responsible for cross-linking peptidoglycan in
Gram-positive_bacteria
Chemical compound
Sulbactam is a β-lactamase inhibitor. This drug is given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that
Sulbactam
Chemical compound
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family. It is a prodrug and has no antibacterial activity itself, but quickly
Hetacillin
Chemical compound
Avibactam is a non-β-lactam β-lactamase inhibitor developed by Actavis (now Teva) jointly with AstraZeneca. A new drug application for avibactam in combination
Avibactam
Organism belonging to kingdom Fungi
antibiotics, including the penicillins, a structurally related group of β-lactam antibiotics that are synthesized from small peptides. Although naturally
Fungus
Chemical compound
((+)-6-aminopenicillanic acid) is an organic compound that is used in the synthesis of β–lactam antibiotics including amoxicillin, ampicillin, oxacillin, and carbenicillin
6-APA
Chemical compound
Tomopenem (formerly CS-023) is a carbapenem β-lactam antibiotic. Sugihara, K.; Tateda, K.; Yamamura, N.; Koga, T.; Sugihara, C.; Yamaguchi, K. (2011).
Tomopenem
Chemical compound
Rifasutenizol is an investigational new drug developed by TenNor Therapeutics, primarily aimed at treating Helicobacter pylori infections. It is a novel
Rifasutenizol
Chemical compound
Tilivalline is a nonribosomal enterotoxin and was the first naturally occurring pyrrolobenzodiazepine (PBD) to be associated with disease in the human
Tilivalline
Chemical compound
reported with beta-lactam antibiotics, including ceftaroline. Exercise caution in people with known hypersensitivity to beta-lactam antibiotics including
Ceftaroline_fosamil
Pharmaceutical
Balcinrenone is an experimental selective mineralocorticoid receptor modulator developed by AstraZeneca for heart failure. Compared to mineralocorticoid
Balcinrenone
Pharmaceutical compound
7-Hydroxyropinirole (developmental code name SK&F-89124 or SKF-89124) is a dopamine receptor agonist and active metabolite of the antiparkinsonian agent
7-Hydroxyropinirole
Benzodiazepine medication
Gidazepam, also known as hydazepam or hidazepam, is a drug which is an atypical benzodiazepine derivative, developed in the Soviet Union. It is a selectively
Gidazepam
LACTAM
LACTAM
LACTAM
LACTAM
Boy/Male
Hindu
Person who brings fame, Famous or glorious
Boy/Male
Indian, Telugu
Lord Ganesh
Girl/Female
Indian, Telugu
Honey
Boy/Male
Muslim
Right, Appropriate, Correct
Surname or Lastname
English
English : variant of Lecatt, which is most probably a variant of Leggett.John Lecatt was born in VA during 1642. His descendants have borne the surnames Lecatt, Lecat, Lecate, Lecates, Lecato, Lekate, Lekates, Lekites, and Legates. The family lived first in Accomack Co., VA. By the 1790s most had moved north to MD and DE.
Surname or Lastname
English
English : variant of Beaumont.Catalan : from the place name Bellmont, a variant of Bellmunt ‘beautiful mountain’. Compare Spanish Belmonte.
Boy/Male
Muslim
The Biblical Noah is the English language equivalent.
Girl/Female
Arabic, Hindu, Indian, Muslim
Most Prettiest Angel of Heaven; Female of the Haven
Boy/Male
Muslim/Islamic
Meteor
Boy/Male
Italian
Dark-skinned; A Moor.
LACTAM
LACTAM
LACTAM
LACTAM
LACTAM
a.
Pertaining to, or designating, an amido acid related to lactic acid, and called also amido-propionic acid.
n.
One of a series of anhydrides of an amido type, analogous to the lactones, as oxindol.
n.
One of a series of anhydrides resembling the lactams, but of an imido type; as, isatine is a lactim. Cf. Lactam.
n.
A white crystalline nitrogenous substance (C8H7NO) of the indol group, obtained by the reduction of dioxindol. It is a so-called lactam compound.
n.
The condition, quality, or relation of metameric substances, or their respective derivatives, which are more or less interchangeable, according as one form or the other is the more stable. It is a special case of metamerism; thus, the lactam and the lactim compounds exhibit tautomerism.
n.
An acid amide derived from lactic acid, and obtained as a white crystalline substance having a neutral reaction. It is metameric with alanine.