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Dimer for protein manipulation
FK1012 is a dimer consisting of two molecules of tacrolimus (FK506) linked via their vinyl groups. It is used as a research tool in chemically induced
FK1012
activation. The first small molecule CID system was developed in 1993 and used FK1012, a derivative of the drug tacrolimus (FK506), to induce homo-dimerization
Chemically induced dimerization
Chemically_induced_dimerization
Protein family
(FKBP1A) does not normally form a dimer but will dimerize in the presence of FK1012, a derivative of the drug tacrolimus (FK506). This has made it a useful
FKBP
Protein and coding gene in humans
v t e PDB gallery 1a7x: FKBP12-FK1012 COMPLEX 1b6c: CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12
FKBP1A
FK1012
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FK1012
Girl/Female
Indian
Rich, Wealthy, Prosperous
Girl/Female
Hindu
Granter of issues
Boy/Male
Hindu
Heaviness
Girl/Female
Tamil
Vishnumaya | விஷà¯à®£à¯à®®à®¾à®¯à®¾
Goddess Parvati
Boy/Male
Tamil
Ekakshara | à®à®•à®¾à®•à¯à®·à®°
He of the single syllable, A name of Lord Ganesh
Girl/Female
Tamil
To Love
Girl/Female
Muslim
Boy/Male
Australian, Chinese, Hindu, Indian, Irish, Korean, Sanskrit
Bending; Decreasing
Female
Hebrew
(דְּבï‹×¨Ö¸×”) Hebrew name DEBOWRAH means "bee." In the bible, this is the name of the nurse of Rebecca, and the prophetess-judge and wife of Lapidoth. Also spelled Devorah.
Boy/Male
Australian, Hindu, Indian, Telugu
Sweet; Caring
FK1012
FK1012
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