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CNOT6L

  • CNOT6L
  • Protein-coding gene in the species Homo sapiens

    transcription complex subunit 6 like is a protein that in humans is encoded by the CNOT6L gene. It is a paralog of CNOT6 and therefore a potential subunit of the

    CNOT6L

    CNOT6L

    CNOT6L

  • CCR4-Not
  • Multiprotein complex used in gene expression

    with preference for polyadenylated mRNA substates. Has a human paralog CNOT6L. CNOT7 33 3′-5′ exonuclease that is partially redundant with CNOT8. CNOT8

    CCR4-Not

    CCR4-Not

    CCR4-Not

  • P-bodies
  • Biomolecular condensates of mRNA and RNA binding proteins found in eukaryotic cells

    Yes CNOT2 CNOT2 Yes CNOT3 CNOT3 Yes CNOT4 CNOT4 Yes CNOT6 CNOT6 Yes CNOT6L CNOT6L Yes CNOT7 CNOT7 Yes CNOT8 CNOT8 Yes CNOT9 CNOT9 No RBFOX1 RBFOX1 Yes

    P-bodies

    P-bodies

  • Endonuclease/Exonuclease/phosphatase family
  • Protein family

    InterPro: IPR000300 2'-PDE; 2-PDE; ANGEL1; ANGEL2; APEX1; APEX2; CCRN4L; CNOT6; CNOT6L; DNASE1; DNASE1L1; DNASE1L2; DNASE1L3; INPP5A; INPP5B; INPP5D; INPP5E; INPPL1;

    Endonuclease/Exonuclease/phosphatase family

    Endonuclease/Exonuclease/phosphatase family

    Endonuclease/Exonuclease/phosphatase_family

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    Subunit 4 yes CNOT6 CNOT6 CCR4-Not Transcription Complex Subunit 6 yes CNOT6L CNOT6L CCR4-Not Transcription Complex Subunit 6L yes CNOT7 CNOT7 CCR4-Not Transcription

    Stress granule

    Stress granule

    Stress_granule

  • Nocturnin
  • Protein-coding gene in the species Homo sapiens

    endonuclease, INPP5B, Sphingomyelin phosphodiesterase, TDP2, PDE12, and CNOT6L. As in the other EEP members, five conserved catalytic residues help coordinate

    Nocturnin

    Nocturnin

    Nocturnin

  • List of human protein-coding genes 2
  • O75175 3275 CNOT4 HGNC:7880; O95628 3276 CNOT6 HGNC:14099; Q9ULM6 3277 CNOT6L HGNC:18042; Q96LI5 3278 CNOT7 HGNC:14101; Q9UIV1 3279 CNOT8 HGNC:9207; Q9UFF9

    List of human protein-coding genes 2

    List_of_human_protein-coding_genes_2

  • Competing endogenous RNA
  • PTEN ceRNAs in prostate cancer, glioblastoma and melanoma. PTEN ceRNAs CNOT6L, VAPA and ZEB2 have been shown to regulate PTEN expression, PI3K signaling

    Competing endogenous RNA

    Competing_endogenous_RNA

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