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ANGIOMOTIN

Angiomotin

Protein-coding gene in the species Homo sapiens

of angiostatin binding proteins, which includes angiomotin, angiomotin-like 1 (AMOTL1) and angiomotin-like 2 (AMOTL2) characterized by coiled-coil domains

Angiomotin

Angiomotin-like protein 1

Protein-coding gene in the species Homo sapiens

Angiomotin-like protein 1 is a protein that in humans is encoded by the AMOTL1 gene. The protein encoded by this gene is a peripheral membrane protein

Angiomotin-like protein 1

Angiomotin-like_protein_1

AMOTL2

Protein-coding gene in the species Homo sapiens

Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene. Angiomotin is a protein that binds angiostatin, a circulating inhibitor

AMOTL2

Cleavage (embryo)

Division of cells in the early embryo

VB, Akimoto K, et al. (July 2013). "Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos". Current Biology

Cleavage (embryo)

Cleavage_(embryo)

Angiostatin

endopeptidase.[which?] Angiostatin is known to bind many proteins, especially to angiomotin and endothelial cell surface ATP synthase but also integrins, annexin

Angiostatin

YAP1

Protein-coding gene in the species Homo sapiens

PMC 4402938. PMID 22525271. Wang W, Huang J, Chen J (February 2011). "Angiomotin-like proteins associate with and negatively regulate YAP1". The Journal

YAP1

Chromosome 11

Human chromosome

protein AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase AMOTL1: angiomotin-like protein 1 AMPD3: encoding enzyme AMP deaminase 3 API5: encoding protein

Chromosome 11

Chromosome_11

Chromosome 3

Human chromosome

arm) of human chromosome 3: ADIPOQ: adiponectin AMOTL2: encoding protein Angiomotin-like protein 2 ARHGAP31: Rho GRPase activating protein 31 BCHE: butyrylcholinesterase

Chromosome 3

Chromosome_3

Stress granule

Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

Subunit ALPK2 ALPK2/HAK Alpha Kinase 2 AMOTL2 AMOTL2/LCCP Angiomotin Like 2 ANKHD1 ANKHD1 Ankyrin Repeat and KH Domain Containing 1 yes ANKRD17

Stress granule

Stress_granule

WWTR1

Protein-coding gene in the species Homo sapiens

Protein Interaction Partner Functional Effects AMOT, Angiomotin Binding sequesters YAP/TAZ in the cytoplasm, inhibiting their function AP-1, Activator

WWTR1

MAGI1

Protein-coding gene in the species Homo sapiens

O, Sinha I, Veitonmäki N, Aase K, Ernkvist M, Holmgren L (Oct 2005). "Angiomotin regulates endothelial cell-cell junctions and cell motility". The Journal

MAGI1

TRAPPC14

Human protein-coding gene on chromosome 7

as one of the interacting proteins. C7orf43 was found to interact with angiomotin-like protein 2 (AMOTL2), also known as Leman Coiled-Coil Protein (LCCP)

TRAPPC14