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Protein-coding gene in the species Homo sapiens
the UCP2 gene. Chromosomal order is 5'-UCP3-UCP2-3'. In contrast to UCP1 and UCP3, which are primarily expressed in adipose and smooth muscle, UCP2 is
UCP2
Mitochondrial protein
type of UCPs are related to thermogenesis. Although UCP2 and UCP3 are closely related to UCP1, UCP2 and UCP3 do not affect thermoregulatory abilities of
Uncoupling_protein
Protein-coding gene in the species Homo sapiens
diseases are linked to UCP2. In the damaged area of the brain after a brain injury, UP2 expression rises. In the brain, UCP2's ultimate role is in neuronal
Brain mitochondrial carrier protein 1
Brain_mitochondrial_carrier_protein_1
French biochemist
at Laval University. This function of UCP2 has been confirmed by the demonstration of a protective role of UCP2 against atherosclerosis. Ricquier has
Daniel_Ricquier
Ability of an organism to keep its body temperature within certain boundaries
book}}: |work= ignored (help) "OMIM entry on human UnCoupling Protein 2 (UCP2)". Online Mendelian Inheritance in Man. Simpson S, Herring PT (9 May 1905)
Thermoregulation
Mammalian protein found in Homo sapiens
was first cloned in 1988. Uncoupling protein two (UCP2), a homolog of UCP1, was identified in 1997. UCP2 localizes to a wide variety of tissues, and is thought
Thermogenin
Chemical compound
S; Shen, R; Lin, CT; Porco Jr, JA; Lowell, BB (2006). "Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced
Genipin
Protein-coding gene in the species Homo sapiens
hand-containing transmembrane protein 1 (Letm1) and uncoupling proteins 2 and 3 (UCP2/3) contribute to two distinct mitochondrial Ca2+ uptake pathways". The Journal
LETM1
American biochemist, pharmaceutical scientist, and entrepreneur
research went on to clone and characterize mitochondrial uncoupling genes UCP2 and UCP3, in collaboration with colleagues from Prague and Beaverton, Oregon)
Louis_Tartaglia
Enzyme
have mild features that respond to diazoxide treatment. FHI-UCP2, caused by mutations in UCP2, is a rare cause of diazoxide-responsive FH1. Hyperammonemia/hyperinsulinism
Glutamate_dehydrogenase_1
Protein family
containing this domain include: HDMCP, MCART1, MCART2, MCART6, MTCH1, MTCH2 UCP1, UCP2, UCP3 SLC25A1, SLC25A3, SLC25A4, SLC25A5, SLC25A6, SLC25A10, SLC25A11, SLC25A12
Mitochondrial_carrier
Metabolic pathway
D, Bouillaud F (January 2000). "The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP". The Biochemical Journal. 345 (Pt 2): 161–179. doi:10
Oxidative_phosphorylation
Protein-coding gene in the species Homo sapiens
upstream of SM-1 (major skeletal muscle site). Chromosomal order is 5'-UCP3-UCP2-3'. Two splice variants have been found for this gene. UCP3 were confirmed
UCP3
Long-term U.S. health study
Song Y, Tinker L, Kuller LH, Liu S (April 2008). "Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational
Women's_Health_Initiative
Family of membrane transport proteins
carrier (SLC25A1, SLC25A2, SLC25A3, SLC25A4, SLC25A5, SLC25A6, UCP1(SLC25A7), UCP2(SLC25A8), UCP3(SLC25A9), SLC25A10, SLC25A11, SLC25A12, SLC25A13, SLC25A14
Solute_carrier_family
Q96RP3 17843 UCN3 HGNC:17781; Q969E3 17844 UCP1 HGNC:12517; P25874 17845 UCP2 HGNC:12518; P55851 17846 UCP3 HGNC:12519; P55916 17847 UEVLD HGNC:30866;
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Topics referred to by the same term
UCPH may refer to: UCP2 University of Copenhagen This disambiguation page lists articles associated with the title UCPH. If an internal link incorrectly
UCPH
American biochemist
Wikidata Q29616477. Jin Zhang; Ivan Khvorostov; Jason S Hong; et al. (15 November 2011). "UCP2 regulates energy metabolism and differentiation potential of human pluripotent
Carla_Koehler
Protein-coding gene in the species Homo sapiens
the Mechanism of Ion Transport Activity of Neuronal Uncoupling Proteins UCP2, UCP4, and UCP5". Biochemistry. 51 (19): 4004–4014. doi:10.1021/bi3003378
Mitochondrial uncoupling protein 4
Mitochondrial_uncoupling_protein_4
Medical diagnostic method
2025). "The Evaluation of Significance of Uncoupling Protein Genes UCP1, UCP2, UCP3, UCP4, UCP5, and UCP6 in Human Adaptation to Cold Climates". Biology
Sum activity of peripheral deiodinases
Sum_activity_of_peripheral_deiodinases
Spanish medical doctor and scientist
carboxylase, Resistin, Senotherapy, Stearoyl-CoA desaturase-1, Uncoupling protein, UCP2, and UCP3.[citation needed] Notable Cambridge scientists with whom Vidal-Puig
Antonio_Vidal-Puig
American biochemist
to the field of neurodegeneration, as Clemons also hopes to explore how UCP2 could be used to control the functions of amylin in neurons to prevent degeneration
Tameka_A._Clemons
British physiologist
2000). "Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced
Barbara_Cannon
American physiologist
"Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice". Experimental Gerontology. 43 (12): 1061–1068
Barbara_A._Horwitz
Austrian physician
E, Strosberg AD, Patsch JR, Krempler F, Patsch W. A polymorphism in the UCP2 gene promoter is protective against obesity in middle-aged humans. Nature
Wolfgang_Patsch
UCP2
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Homage
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An efficient horse rider
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Lord Shiva
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Maker of Arrows; Diminutive of Fletcher
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rules by the spear.
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Own Light; Gods Gift
UCP2
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UCP2