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TRPM1

  • TRPM1
  • Protein-coding gene in humans

    channel subfamily M member 1 is a protein that in humans is encoded by the TRPM1 gene. The protein encoded by this gene is a member of the transient receptor

    TRPM1

    TRPM1

    TRPM1

  • Nyctalopia
  • Condition making it difficult or impossible to see in relatively low light

    that both CSNB and leopard complex spotting patterns are linked to the TRPM1 gene. The region on horse chromosome 1 to which the Lp gene has now been

    Nyctalopia

    Nyctalopia

    Nyctalopia

  • Appaloosa
  • American horse breed noted for spotted color pattern

    when LP is present. LP is an autosomal incomplete dominant mutation in the TRPM1 gene located at horse chromosome 1 (ECA 1). All horses with at least one

    Appaloosa

    Appaloosa

    Appaloosa

  • TRPM
  • Family of transport proteins

    to form tetramers. The TRPM family consists of eight different channels, TRPM1–TRPM8. Unlike the TRPC and TRPV sub-families, TRPM subunits do not contain

    TRPM

    TRPM

  • Leopard complex
  • Coat pattern in horses

    team mapped the Lp gene to a transient receptor potential channel gene, TRPM1 or Melastatin 1 (MLSN1). The leopard complex allele contains a 1378 bp long

    Leopard complex

    Leopard complex

    Leopard_complex

  • Congenital stationary night blindness
  • Medical condition

    CSNB has been identified in horses and dogs as the result of mutations in TRPM1 (Horse, "LP"), GRM6 (Horse, "CSNB2"), and LRIT3 (Dog, CSNB). Congenital

    Congenital stationary night blindness

    Congenital stationary night blindness

    Congenital_stationary_night_blindness

  • Pregnenolone sulfate
  • Chemical compound

    sulfate is an agonist of the sigma receptor, as well as an activator of the TRPM1 and TRPM3 channels. It may also interact with potassium channels and voltage-gated

    Pregnenolone sulfate

    Pregnenolone sulfate

    Pregnenolone_sulfate

  • Botai culture
  • Archaeological culture of northern Central Asia

    through the use of reins or bridles), and horse remains were found with the TRPM1 coat-colour locus, which causes leopard-spotted coats. Horses with two copies

    Botai culture

    Botai_culture

  • Horse genome
  • DNA profile of a horse

    indicated that both CSNB and leopard complex spotting patterns are linked to TRPM1. As this disorder also afflicts humans, a researcher and lead author from

    Horse genome

    Horse genome

    Horse_genome

  • Index of biophysics articles
  • Index of articles on biophysics

    TPCN2 TRPA (channel) TRPC TRPC1 TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1

    Index of biophysics articles

    Index_of_biophysics_articles

  • Transient receptor potential channel
  • Class of transport proteins

    split into two major clades, αTRPM and βTRPM. αTRPMs include vertebrate TRPM1, TRPM3, and the "chanzymes" TRPM6 and TRPM7, as well as the only insect

    Transient receptor potential channel

    Transient_receptor_potential_channel

  • TRPV
  • Subgroup of TRP cation channels named after the vanilloid receptor

    expression of TRP proteins often leads to tumorigenesis, clearly seen in TRPM1. Particularly high levels of TRPV6 in prostate cancer have been noted. Such

    TRPV

    TRPV

    TRPV

  • Equine coat color genetics
  • Genetics behind the equine coat color

    since then living homozygous roan horses have been found. n/n: No roan. TRPM1 (Leopard complex) LP n Appaloosa or Leopard spotting gene. Produces coat

    Equine coat color genetics

    Equine coat color genetics

    Equine_coat_color_genetics

  • Microphthalmia-associated transcription factor
  • Mammalian protein found in humans

    "Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma". Cancer Research. 64 (2): 509–16.

    Microphthalmia-associated transcription factor

    Microphthalmia-associated transcription factor

    Microphthalmia-associated_transcription_factor

  • Dominant white
  • Horse coat color and its genetics

    Ernest Bailey; Bruce Grahn (August 2008). "Differential Gene Expression of TRPM1, the Potential Cause of Congenital Stationary Night Blindness and Coat Spotting

    Dominant white

    Dominant white

    Dominant_white

  • Metabotropic glutamate receptor 6
  • Mammalian protein found in humans

    for initiating a signaling cascade that ultimately controls gating of the TRPM1 channel. In human patients, mutations in the GRM6 gene are associated with

    Metabotropic glutamate receptor 6

    Metabotropic glutamate receptor 6

    Metabotropic_glutamate_receptor_6

  • Cation channel superfamily
  • Family of ion channel proteins

    of voltage gated ion channels. TRPC1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7 TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4;

    Cation channel superfamily

    Cation channel superfamily

    Cation_channel_superfamily

  • List of human protein-coding genes 8
  • A6NMA1 17477 TRPC6 HGNC:12338; Q9Y210 17478 TRPC7 HGNC:20754; Q9HCX4 17479 TRPM1 HGNC:7146; Q7Z4N2 17480 TRPM2 HGNC:12339; O94759 17481 TRPM3 HGNC:17992;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • List of OMIM disorder codes
  • 610427; CABP4 Night blindness, congenital stationary, type IC; 613216; TRPM1 Night blindness, congenital stationary, X-linked, type 2A; 300071; CACNA1F

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

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Online names & meanings

  • Manon
  • Girl/Female

    Australian, Danish, Dutch, French, German, Hebrew, Netherlands, Swiss

    Manon

    Bitterness; Diminutive Form of Marie; Similar to Mary Bitter

  • VICTOIRE
  • Female

    French

    VICTOIRE

    French form of Latin Victoria, VICTOIRE means "conqueror" or "victory."

  • LAGMAN
  • Male

    Swedish

    LAGMAN

    Medieval Swedish form of Old Norse Lögmaðr, LAGMAN means "lawman."

  • Furrina
  • Girl/Female

    Latin

    Furrina

    Furies.

  • CUONG
  • Male

    Vietnamese

    CUONG

    Vietnamese name CUONG means "flourishing, healthy."

  • Teed
  • Surname or Lastname

    English

    Teed

    English : unexplained.

  • Satwika
  • Girl/Female

    Indian, Telugu

    Satwika

    God of Mather

  • Trang
  • Boy/Male

    Hindu, Indian, Vietnamese

    Trang

    Dawn; Decorated; Honored

  • Allah
  • Boy/Male

    Indian

    Allah

    Allah

  • PARI
  • Female

    Persian/Iranian

    PARI

    (پری) Persian name PARI means "fairy."

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