AI & ChatGPT searches , social queriess for STAT6
Search references for STAT6. Phrases containing STAT6
See searches and references containing STAT6!
Search references for STAT6. Phrases containing STAT6
See searches and references containing STAT6!STAT6
Protein and coding gene in humans
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that belongs to the Signal Transducer and Activator of Transcription
STAT6
Biological signaling pathway h
are seven STAT proteins: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. STAT proteins contain many different domains, each with a different function
JAK-STAT_signaling_pathway
Epithelial cells that secrete mucins
initiates a STAT6 signalling response. Binding of IL-13 causes phosphorylation of tyrosine residues at the IL-4Rα. This results in docking of STAT6 monomers
Goblet_cell
Protein-coding gene in the species Homo sapiens
mechanisms. It has been shown to activate downstream transcription factors STAT6 and IRF3 through TBK1, which are responsible for antiviral response and
Stimulator of interferon genes
Stimulator_of_interferon_genes
Protein and coding gene in humans
the type 2 IL-4 receptor. Heterodimerization activates both the STAT6 and the IRS. STAT6 signaling is important in initiation of the allergic response.
Interleukin_13
Protein-coding gene in the species Homo sapiens
the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL13RA1 expression has been linked to higher survival
Interleukin 13 receptor, alpha 1
Interleukin_13_receptor,_alpha_1
Cell surface receptors for interleukin-13
Transcription (STAT) pathway, resulting in phosphorylation of STAT6. Phosphorylated STAT6 dimerises and acts as a transcription factor activating many
Interleukin-13_receptor
Mammalian protein found in humans
interleukin 4 (IL-4) produced by T cells can induce CD20 expression via STAT6 transcription factor. CD20 is expressed on all stages of B cell development
CD20
Technique used in mass spectroscopy
and drugs which are inhibitors of the enzyme. Competition studies between STAT6 and inhibitors have used ESI as a way to screen for potential new drug candidates
Electrospray_ionization
Medical condition
Recurrent somatic fusions of the two genes, NGFI-A–binding protein 2 (NAB2) and STAT6, located at chromosomal region 12q13, have been identified in solitary fibrous
Solitary_fibrous_tumor
Protein-coding gene in the species Homo sapiens
upstream activation of STAT6. An independent study confirmed the effect of PGC-1 on polarisation of macrophages towards M2 via STAT6/PPAR gamma and furthermore
PGC-1α
Family of transport proteins
be yielded, interacting with transcriptional activator and co-activator STAT6 and p100, or components of the canonical Wnt signaling pathway in an inhibitory
Polycystin_1
Immune system response to a substance that most people tolerate well
PDCH1, COL29A1), mediating immune cell function (PHF11, H1R, HDC, TSLP, STAT6, RERE, PPP2R3C), and influencing susceptibility to allergic sensitization
Allergy
Mammalian protein found in Mus musculus
regeneration cascade through phosphorylation of its intracellular effector STAT6 in an experimental Alzheimer's disease model in adult zebrafish brain. IL-4
Interleukin_4
Cancer originating in lymph nodes
proliferation, and, in ≤15% of cases several other genes including MEF2B, STAT6, EP300, ARID1A, SLC22A2, CARD11, FOXO1, GNA12, B2M (i.e. the gene for beta-2
Follicular_lymphoma
Protein and coding gene in humans
gliomas. SND1 has been shown to interact with MYB, PIM1, POLR2A, RBPJ, and STAT6. SND1 also interacts with G3BP (stress granule protein) and AEG-1. GRCh38:
SND1
Sub-population of CD4+T cells
commitment and to IL-9 production. STAT6 is activated by signaling through IL-4 receptor. Once activated, phosphorylated STAT6 mediate the transcription of
Th_9_cell
Type of immune cell
cells, and IL-4/IL-5 CD4 T cells. The key Th2 transcription factors are STAT6 and GATA3. IL-4 is the positive feedback cytokine for Th2 cells differentiation
Helper_T_cell
Medical condition
the STAT6 gene to produce a (NAB2)-STAT6 chimeric gene whose fusion protein product is detected by specific immunohistochemistry assays for STAT6 protein
Mammary_myofibroblastoma
Family of intracellular transcription factors
identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1 homodimers are involved in type II interferon signalling, and bind
STAT_protein
Protein-coding gene in the species Homo sapiens
protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6. STAT proteins are key activators of gene transcription which bind to DNA
STAT4
Protein-coding gene in the species Homo sapiens
PTMA, PPARA, PPARG, RORA, RELA, SMAD1, SMAD2, SMAD7, SNIP1, SS18, STAT3, STAT6, TAL1, TCF3, TFAP2A, TGS1, TRERF1, TSG101, THRA, TWIST1, YY1, and Zif268
EP300
Heterodimeric receptor
proteins (classically STAT1, STAT2, or STAT3, although STAT4, STAT5, and STAT6 may play a role in certain cell types) via their SH2 domains. Once recruited
Interferon-alpha/beta receptor
Interferon-alpha/beta_receptor
Predisposition towards allergy
tried to map susceptibility genes for atopy. Genes for atopy (C11orf30, STAT6, SLC25A46, HLA-DQB1, IL1RL1/IL18R1, TLR1/TLR6/TLR10, LPP, MYC/PVT1, IL2/ADAD1
Atopy
Protein domain
SOCS5; SOCS6; SOCS7 SRC; SRMS STAT1; STAT2; STAT3; STAT4; STAT5A; STAT5B; STAT6 SUPT6H; SYK TEC; TENC1; TNS; TNS1; TNS3; TNS4; TXK VAV1; VAV2; VAV3 YES1;
SH2_domain
Protein-coding gene in the species Homo sapiens
Recurrent somatic fusions of the two genes, NGFI-A–binding protein 2 (NAB2) and STAT6, located at chromosomal region 12q13, have been identified in solitary fibrous
NAB2
ENSG00000173757 STAT Known motif – In vivo/Misc source [890] ADTTCYHRGAAA STAT6 ENSG00000166888 STAT Known motif – In vivo/Misc source [891] DWTTYCNDDGAA
List of human transcription factors
List_of_human_transcription_factors
Protein-coding gene in Homo sapiens
M, Pernis AB (October 1999). "IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells". Journal of Immunology. 163 (7):
STAT2
Human protein and coding gene
Salmonella, and against Streptococcus pneumoniae infections by activating STAT6 and SPDEF. Among viruses, it has been associated with infection by hepatitis
NLRP3
Cytokine with structural similarity to Interleukin-2
and IL-2. When IL-15 binds its receptor, JAK kinase, STAT3, STAT5, and STAT6 transcription factors are activated to elicit downstream signaling events
Interleukin_15
Component of the innate immune system
transcription factors IRF3, which induces the type 1 IFN response, and STAT6, which induces chemokines such as CCL2 and CCL20 independently of IRF3.
CGAS–STING cytosolic DNA sensing pathway
CGAS–STING_cytosolic_DNA_sensing_pathway
Protein-coding gene in humans
NFKB2, NFKBIE, NOTCH1, Nuclear receptor coactivator 1, RELA, RELB, STAT3, STAT6, and TSC22D3. GRCh38: Ensembl release 89: ENSG00000109320 – Ensembl, May
NFKB1
Protein-coding gene in the species Homo sapiens
PPARGC1A, Peroxisome proliferator-activated receptor alpha, SNW1, STAT3, STAT6, TRIP4, and Thyroid hormone receptor beta. GRCh38: Ensembl release 89: ENSG00000084676
Nuclear receptor coactivator 1
Nuclear_receptor_coactivator_1
mediate signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4 CD213a2 IL13RA2 - Interleukin-13 receptor subunit
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Medical condition
cases; desmin protein in 22% of cases; ACTA2 (also termed α-SMA), CD34, and STAT6 proteins in 10% or fewer cases, and S100 and cytokeratin proteins in no
Angiofibroma_of_soft_tissue
Protein-coding gene in the species Homo sapiens
deletion in microglia/macrophages ameliorates brain injury through the STAT6/PPARγ pathway in ischemic stroke". CNS Neuroscience & Therapeutics. 30 (8):
S100A9
Tumor, Presenting as a Cystic Mass, Showing NAB2ex4-STAT6ex2 Fusion and STAT6 Immunostaining". International Journal of Gynecological Pathology. 38 (1):
List_of_vaginal_tumors
Protein-coding gene in the species Homo sapiens
BCL6, CD40, GM-CSF, IL-4, Ikaros, IRF8, JMJD3, MMP12, NFATC2, SPI1, and STAT6. Interferon regulatory factors GRCh38: Ensembl release 89: ENSG00000137265
IRF4
Protein-coding gene in humans
regulator of T-cell activation. BHLHE41 upregulates CD25 expression through a Stat6-dependent mechanism, which enhances the IL-2 receptor-mediated signal pathway
BHLHE41
Protein-coding gene in humans
factor 1 (EBF1) is required for the expression of SLAMF1 gene in B cells. STAT6, IRF4, and NF-kB factors involved in the transfer of the signals from the
SLAMF1
Protein-coding gene in the species Homo sapiens
highly restricted to CD4+ T-cells and induced by interleukin-4-activated STAT6 pathway". Hum. Immunol. 68 (8): 708–14. doi:10.1016/j.humimm.2007.04.008
G6B
example, interleukin-4 can promote the activation of transcription factor STAT6 by phosphorylation. This can then trigger expression of matrix metalloproteinase
Fusion_mechanism
Group of cytokine proteins
and structure. They also used the same type II IL-4 receptor to activate STAT6. Similar functions have IL-1 to Th17 cells and IL-18 to Th1 lymphocytes
Interleukin-1_family
Pharmaceutical compound
suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt". Biomedicine & Pharmacotherapy. 168 115774. doi:10.1016/j.biopha
GSK137647A
authors list (link) "signal transducer and activator of transcription 6 (STAT6) [Homo sapiens]". NCBI Gene. Lee DK, Suh D, Edenberg HJ, Hur MW. (2002)
Glutamate-rich_protein_4
Protein-coding gene in the species Homo sapiens
(September 2002). "Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II". EMBO J. 21 (18): 4950–8. doi:10.1093/emboj/cdf463
POLR2A
Medical condition
INI-1 and SNF5) proteins but typically fail to express CD34, S-100, CD34, STAT6, CD68, CD56, cytokeratin, ERG, β-catenin, or myogenin proteins. The epithelioid
Low-grade myofibroblastic sarcoma
Low-grade_myofibroblastic_sarcoma
Turkish neuroscientist and geneticist (born 1981)
Dresden press release", TU Dresden, April 22, 2019 Bhattarai, P. (2016). "IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon
Çağhan_Kızıl
Addition of one or more ADP-ribose moieties to a protein
regards to cancer therapy targets; it is a signal transducer and activator of STAT6 transcription-interacting protein, and was shown to be associated with the
ADP-ribosylation
Human protein-coding gene
"Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene"
HIST2H3C
Q14765 15955 STAT5A HGNC:11366; P42229 15956 STAT5B HGNC:11367; P51692 15957 STAT6 HGNC:11368; P42226 15958 STATH HGNC:11369; P02808 15959 STAU1 HGNC:11370;
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Protein-coding gene in humans
exhibits an upregulating effect in PIGR expression because of the presence of STAT6 enhancer, the main downstream effector of IL-4, binding site in PIGR's intron
Polymeric immunoglobulin receptor
Polymeric_immunoglobulin_receptor
Protein-coding gene in the species Homo sapiens
in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism". J Immunol. 170
RETNLB
Alveolar macrophages whose characteristics have been affected by smoking
multiple STAT proteins activities. In response to the smoking, STAT3 and STAT6 signaling are stimulated to potentiate M2-like phenotype with elevated IL-6
Smoker's_macrophages
Aspect of molecular biology
Schleimer, R. P. (1999). "Activation of Eotaxin Gene Transcription by NF-κB and STAT6 in Human Airway Epithelial Cells". J Immunol 163:6876-6883. PMID 10586089
Promoter_bashing
Protein-coding gene in the species Homo sapiens
(2003). "Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling". J. Biol. Chem. 278 (5): 2787–2791. doi:10.1074/jbc.M210196200
PPAP2A
Mammalian protein found in Homo sapiens
N, et al. (Feb 2016). "Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation". Scientific Reports
LYN
Pharmaceutical compound
pro-inflammatory mediators induce nitric oxide synthase (iNOS) through STAT1 and STAT6 in epithelial cells. Basal FENO could be more dependent on up-regulation
Pitrakinra
Macrophage subset
generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling". Journal of Leukocyte Biology. 98 (3): 395–407. doi:10.1189/jlb
Regulatory_macrophages
Enzymes that catalyze acyl group transfer from acetyl-CoA to histones
endonuclease-1, thymine DNA glycosylase, and Werner syndrome DNA helicase, STAT6, Runx1 (AML1), UBF, Beta2/NeuroD, CREB, c-Jun, C/EBPβ, NF-E2, SREBP, IRF2
Histone_acetyltransferase
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
List of MeSH codes (D12.776.930)
List_of_MeSH_codes_(D12.776.930)
Protein-coding gene in the species Homo sapiens
interaction of a transcription factor, LPS-induced TNF-alpha factor, and STAT6(B) with effects on multiple cytokines". Proc. Natl. Acad. Sci. U.S.A. 102
LITAF
Protein-coding gene in the species Homo sapiens
suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation". Proc. Natl. Acad. Sci. U.S.A. 99 (20):
SOCS5
hypermutation Specific granule Specol STAT protein STAT1 STAT2 STAT3 STAT4 STAT5 STAT6 Stem cell educator Stimulator of interferon genes Stromal cell-derived factor
Index_of_immunology_articles
Protein-coding gene in the species Homo sapiens
requires NF-κB interaction with other transcription factors, such as STAT (see STAT6), AP-1 (JUN), and NFAT (see NFATC1). NFKBIE has been shown to interact with
NFKBIE
Australian-American immunologist and biochemist
; Ihle, J. N.; Wynn, T. A.; Murray, P. J. (2001-02-15). "Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production". Journal
Peter_Murray_(immunologist)
Medical condition
2014). "Diagnostic utility of NCOA2 fluorescence in situ hybridization and Stat6 immunohistochemistry staining for soft tissue angiofibroma and morphologically
Cellular_angiofibroma
024.421.500 – stat5 transcription factor MeSH D12.776.476.024.421.600 – stat6 transcription factor MeSH D12.776.476.024.500.500 – tnf receptor-associated
List of MeSH codes (D12.776.476)
List_of_MeSH_codes_(D12.776.476)
057.186.500 – stat5 transcription factor MeSH D12.776.157.057.186.600 – stat6 transcription factor MeSH D12.776.157.057.500.500 – tnf receptor-associated
List of MeSH codes (D12.776.157)
List_of_MeSH_codes_(D12.776.157)
024.342.500 – stat5 transcription factor MeSH D12.644.360.024.342.600 – stat6 transcription factor MeSH D12.644.360.024.374 – suppressor of cytokine signaling
List_of_MeSH_codes_(D12.644)
STAT6
STAT6
STAT6
STAT6
Boy/Male
Tamil
Rajahamsan | ராஜாஹமà¯à®¸à®¨
Swan
Boy/Male
Indian
One who laughs often
Surname or Lastname
English
English : habitational name from Feering, a village in Essex, named from the Old English personal name Fēra + -ingas ‘people of’, i.e. ‘(settlement of) Fēra’s people’.Americanized spelling of German Viering, a topographic name for someone from a swampy area, from a derivative of Germanic vir ‘bog’, ‘swamp’, or a variant of Fehring 2.
Male
Finnish
Pet form of Finnish Taneli, TATU means "God is my judge."
Boy/Male
Arabic, Muslim
A Great Sahabi who is the Narrator of Many Traditions
Boy/Male
Tamil
An epithet of Shiva
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
A Cobra
Boy/Male
Hindu
Boy/Male
Afghan, African, American, Arabic, Chinese, French, Hindu, Indian, Kannada, Muslim, Pashtun, Sindhi, Swahili
Devotee of God; Lustrous; Shiny; Brightest; Most Brilliant; More Radiant
Girl/Female
Arabic, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Sindhi, Tamil, Telugu
Grand; Splendid; Big; Goddess Parvati / Durga; Polite; Marvellous; Very Large
STAT6
STAT6
STAT6
STAT6
STAT6