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SPRED1

  • SPRED1

    • Protein-coding gene in the species Homo sapiens

    protein 1 (pronounced spread-1) is a protein that in humans is encoded by the SPRED1 gene located on chromosome 15q13.2 and has seven coding exons. SPRED-1 is

    SPRED1

    SPRED1

    SPRED1

  • Legius syndrome

    • Medical condition

    mistaken for neurofibromatosis type I. It is caused by mutations in the SPRED1 gene. It is also known as neurofibromatosis type 1-like syndrome. Nearly

    Legius syndrome

    Legius syndrome

    Legius_syndrome

  • Leukemia

    • Type of cancer

    anemia is a risk factor for developing acute myeloid leukemia. Mutation in SPRED1 gene has been associated with a predisposition to childhood leukemia. Inherited

    Leukemia

    Leukemia

    Leukemia

  • Lists of human genes

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    Lists of human genes

    Lists_of_human_genes

  • List of syndromes

    • Syndromes

    syndrome Splenic flexure syndrome Split hand syndrome Spondylo-ocular syndrome SPRED1 Staphylococcal scalded skin syndrome STAR syndrome Stauffer syndrome Stendhal

    List of syndromes

    List_of_syndromes

  • RASopathy

    • Family of genetic conditions caused by mutations affecting Ras genes

    RASA1 RASA2 SYNGAP1 SOS1 SOS2 CBL PTPN11 BRAF RAF1 MAP2K1 MAP2K2 MAP3K8 SPRED1 SPRY1 MYST4 LZTR1 A2ML1 Boxel-Woolf, Tom Van; McCarthy, Kathleen M. (2025)

    RASopathy

    RASopathy

  • List of OMIM disorder codes

    • ventricular noncompaction, X-linked; 300183; TAZ Legius syndrome; 611431; SPRED1 Leigh syndrome due to cytochrome c oxidase deficiency; 256000; COX15 Leigh

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

  • SPR domain

    • Protein family

    proteins. Human genes encoding protein containing the SPR domain include: SPRED1, SPRED2, SPRED3, SPRY1, SPRY2, SPRY3, SPRY4 Zhang S, Lin Y, Itäranta P,

    SPR domain

    SPR_domain

  • Sally Temple

    • American neuroscientist

    into treatments for both macular degeneration and Parkinson's disease. Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones

    Sally Temple

    Sally_Temple

  • T-cell acute lymphoblastic leukemia

    • Type of acute lymphoblastic leukemia

    suppressor gene, thereby increasing the risk of T-ALL. Mutations in the SPRED1 gene are also associated with the development of T-ALL. Patients with immature

    T-cell acute lymphoblastic leukemia

    T-cell acute lymphoblastic leukemia

    T-cell_acute_lymphoblastic_leukemia

  • SPRY2

    • Protein-coding gene in the species Homo sapiens

    have enhanced inhibition. SPRY2 has been shown to interact with Cbl gene. SPRED1 gene Neurofibromin 1 SPRY1 GRCh38: Ensembl release 89: ENSG00000136158 –

    SPRY2

    SPRY2

    SPRY2

  • Shapiro–Senapathy algorithm

    • Gaetano; Eoli, Marica (19 June 2020). "Simultaneous Detection of NF1, SPRED1, LZTR1, and NF2 Gene Mutations by Targeted NGS in an Italian Cohort of Suspected

    Shapiro–Senapathy algorithm

    Shapiro–Senapathy algorithm

    Shapiro–Senapathy_algorithm

  • SPRY1

    • Protein-coding gene in the species Homo sapiens

    a protein that in humans is encoded by the SPRY1 gene. Neurofibromin 1 SPRED1 GRCh38: Ensembl release 89: ENSG00000164056 – Ensembl, May 2017 GRCm38:

    SPRY1

    SPRY1

    SPRY1

  • List of human protein-coding genes 8

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • List of human protein-coding genes 1

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 1

    List_of_human_protein-coding_genes_1

  • SPRED2

    • Protein-coding gene in the species Homo sapiens

    1016/j.bbrc.2006.10.150. PMID 17094949. GeneReviews/NIH/NCBI/UW entry on Legius syndrome SPRED1 Sprouty-related, EVH1 domain-containing protein 1 v t e

    SPRED2

    SPRED2

    SPRED2

  • Neurofibromin

    • Mammalian protein found in humans

    suggesting it represents a promising therapeutic target. Merlin (protein) SPRED1 gene GRCh38: Ensembl release 89: ENSG00000196712 – Ensembl, May 2017 GRCm38:

    Neurofibromin

    Neurofibromin

    Neurofibromin

  • List of human protein-coding genes 5

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • FAM98C

    • Gene

    been predicted to interact with DR1, LRRCC1, FAM83F, TMEM256, Pdrm16 and SPRED1. LRRCC1 and TMEM256 were both mentioned with FAM98C as potentially novel

    FAM98C

    FAM98C

    FAM98C

  • List of human protein-coding genes 7

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • WH1 domain

    • Protein domain

    containing the WH1 (EVH1) domain include: ENAH, EVL HOMER1, HOMER2, HOMER3 SPRED1, SPRED2, SPRED3 VASP, WAS, WASL Symons M, Derry JM, Karlak B, Jiang S, Lemahieu

    WH1 domain

    WH1_domain

  • List of human protein-coding genes 2

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 2

    List_of_human_protein-coding_genes_2

  • List of human protein-coding genes 6

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

  • List of human protein-coding genes 3

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • List of human protein-coding genes 9

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 9

    List_of_human_protein-coding_genes_9

  • List of human protein-coding genes 4

    • genes RBM12B–SPR  •List of human protein-coding genes page 8 covers genes SPRED1–USP17L29  •List of human protein-coding genes page 9 covers genes USP17L30–ZZZ3

    List of human protein-coding genes 4

    List_of_human_protein-coding_genes_4

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Online names & meanings

  • Tanik

    • Boy/Male

    Indian, Russian, Turkish

    Tanik

    Little

  • Gatravati

    • Girl/Female

    Indian, Sanskrit

    Gatravati

    Story; Narration

  • Bevan

    • Boy/Male

    Christian, English

    Bevan

    Son of God

  • Fugit

    • Surname or Lastname

    English

    Fugit

    English : variant spelling of Fugett.

  • Asvald

    • Boy/Male

    Norse

    Asvald

    Son of Ulf.

  • Miftah |

    • Boy/Male

    Muslim

    Miftah |

    Key

  • Roderick

    • Surname or Lastname

    English

    Roderick

    English : from the personal name Hrōdrīc, composed of hrōd ‘renown’ + rīc ‘power(ful)’, Old Norse form Hroþrekr. This name was in use among the Normans in the form Rodric, but was not frequent in the medieval period.Welsh : Anglicized form of the personal name Rhydderch, originally a byname meaning ‘reddish brown’.

  • Divyang | திவ்யாஂக

    • Boy/Male

    Tamil

    Divyang | திவ்யாஂக

    Divine body

  • RAIMUNDE

    • Female

    French

    RAIMUNDE

    Feminine form of Norman French Raimund, RAIMUNDE means "wise protector."

  • Anunay | அநுநாய 

    • Boy/Male

    Tamil

    Anunay | அநுநாய 

    Supplication, Consolation

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SPRED1

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