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SPNS2

SPNS2

Protein-coding gene in the species Homo sapiens

Spinster homolog 2 (Drosophila) is a protein that in humans is encoded by the SPNS2 gene. The orthologous protein in zebrafish has been shown to transport

SPNS2

Solute carrier family

Family of membrane transport proteins

transporters (ANKH(SLC62A1)) Sphingosine-phosphate transporters (SPNS1(SLC63A1), SPNS2(SLC63A2), SPNS3(SLC63A3)) Golgi Ca2+/H+ exchangers (TMEM165(SLC64A1)) NPC-type

Solute carrier family

Solute_carrier_family

Atypical SLCs

phylogenetic closeness. Some Atypical SLC of MFS type are: OCA2, CLN3, SPNS1, SPNS2, SPNS3, SV2A, SV2B, SV2C, SVOP, SVOPL, MFSD1, MFSD2A, MFSD2B, MFSD3, MFSD4A

Atypical SLCs

Atypical_SLCs

Mouse Genetics Project

that influence bone strength. Mutation of CENPJ models Seckel syndrome. SPNS2 is important in mammalian immune system function. MYSM1 is important for

Mouse Genetics Project

Mouse_Genetics_Project

Centre for Medicines Discovery

UK academic institution

and inhibition of the immunoregulatory sphingosine-1-phosphate exporter SPNS2". Vol. Behind the Paper. SpringerNature. Retrieved 19 February 2026. SGC

Centre for Medicines Discovery

Centre_for_Medicines_Discovery

List of human protein-coding genes 7

A0A1B0GTD5 15730 SPN HGNC:11249; P16150 15731 SPNS1 HGNC:30621; Q9H2V7 15732 SPNS2 HGNC:26992; Q8IVW8 15733 SPNS3 HGNC:28433; Q6ZMD2 15734 SPO11 HGNC:11250;

List of human protein-coding genes 7

List_of_human_protein-coding_genes_7

Major facilitator superfamily

Protein family

MFSD14A, MFSD14B, UNC93A, UNC93B1, SV2A, SV2B, SV2C, SVOP, SVOPL, SPNS1, SPNS2, SPNS3 and CLN3. As there is high sequence identity and phylogenetic resemblance

Major facilitator superfamily