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Protein-coding gene in humans
subunit A, flavoprotein variant is a protein that in humans is encoded by the SDHA gene. This gene encodes a major catalytic subunit of succinate-ubiquinone
SDHA
Enzyme
flavoprotein (SDHA) and an iron-sulfur protein (SDHB), form a hydrophilic head where enzymatic activity of the complex takes place. SDHA contains a covalently
Succinate_dehydrogenase
Medical condition
(SDH). SDH plays a key role in metabolism; the catalytic end, made up of SDHA and SDHB oxidizes succinate to fumarate in the tricarboxylic acid (TCA) cycle
Mitochondrial complex II deficiency
Mitochondrial_complex_II_deficiency
Protein-coding gene in the species Homo sapiens
succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of
SDHB
Metabolic disease
syndrome are located on chromosome 2 (BCS1L and NDUFA10); chromosome 5 (SDHA, NDUFS4, NDUFAF2, and NDUFA2); chromosome 8 (NDUFAF6), chromosome 10 (COX15);
Leigh_syndrome
Condition involving an enlarged, ineffective heart
also shown pathogenicity for dilated cardiomyopathy, designated 1GG for SDHA. Kayvanpour et al. performed 2016 a meta-analysis with the largest dataset
Dilated_cardiomyopathy
Species of bacterium
and cannot replicate within cells, while deletion of the Dot/Icm effector SdhA results in destabilization of the vacuolar membrane and no bacterial replication
Legionella_pneumophila
Tumor of the adrenal medulla which secretes adrenal hormones
neck paraganglioma, pheochromocytoma, gastrointestinal stromal tumor PGL5 SDHA 10–15% Low Pheochromocytoma, head and neck paraganglioma, gastrointestinal
Pheochromocytoma
Rare neuroendocrine tumour
genes for the succinate dehydrogenase, SDHD (previously known as PGL1), SDHA, SDHC (previously PGL3) and SDHB have been identified as causing familial
Paraganglioma
List of German Schutzstaffel members
27 July 1915 193096 Rudolf Neugebauer Born 21.12.1912. Usf 12.3.38 with SDHA 1938; 1941, promotion to KK of KK z.Pr. Neugebauer, Stapo Darmstadt. BBL
List_of_SS_personnel
Energy-producing metabolic pathway
Complex II consists of four protein subunits: succinate dehydrogenase (SDHA); succinate dehydrogenase [ubiquinone] iron–sulfur subunit mitochondrial
Electron_transport_chain
Study of cell metabolism in the development of cancer
Brain cancer, Leukemia Succinate Inhibits 2-oxoglutarate-dependent oxygenase SDHA,SDHB,SDHC,SDHD,SDHAF1,SDHAF2 succinate dehydrogenase Renal and Thyroid tumors
Oncometabolism
Protein-coding gene in humans
flavination of SDH1 (SDHA), another subunit of the SDH complex. It does so by incorporating the flavin adenine dinucleotide (FAD) cofactor into SDHA. Such flavination
SDHAF2
Muscle disorders caused by mitochondrial dysfunction
(Succinate CoQ reductase deficiency; succinate dehydrogenase deficiency) SDHA, SDHAF1, SDHD, SDHB AR PS252011 cytochrome b of complex III (MTCYB); Exercise
Mitochondrial_myopathy
Protein found in humans
the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit. The SDHC protein is one of four nuclear-encoded subunits that comprise
Succinate dehydrogenase complex subunit C
Succinate_dehydrogenase_complex_subunit_C
Gene which maintains basic cellular functions
dehydrogenase TALDO1 Transaldolase in pentose shunt TSTA3 Mannose metabolism SDHA NM_004168 Succinate Dehydrogenase subunit A SDHAF2 NM_017841 SDHB NM_002973
Housekeeping_gene
Letter "Ṣa" in Indic scripts
rakar र (ra) gives the ligature ṣkra: ष্ (ṣ) + ढ (ḍʱa) gives the ligature ṣḍʱa: ष্ (ṣ) + न (na) gives the ligature ṣna: ष্ (ṣ) + त (ta) gives the ligature
Ṣa_(Indic)
German SS officer during the Nazi era
1086615). In 1938, he joined the SS (SS number: 266047) and worked for the SDHA (Sicherheitsdiensthauptamt), the headquarters of the intelligence agency
Rudolf_Neugebauer
Indian Islamic leader (born 1959)
"Siqat ud-Da'wat il-Haadiyat il-'Alaviyah" (ثقۃ الدعوۃ الهادیۃ العلویۃ, SDHA) meaning the most trusted, and Ra's ul-Hudood was awarded a special laqab
Haatim_Zakiyuddin
like lexA mutations. Synthetic rescue was engineered in E.coli by deleting sdhA and compensating with mutations in icd for the purpose of rescuing lethal
Synthetic_rescue
Protein superfamily
Complex II, SDHB plays a central role in transferring electrons from subunit SDHA to ubiquinone via its three iron–sulfur clusters. HSC20 recognizes and binds
LYRM_protein
RNA family
sdhA and sdhC. NrrF acts as an antisense RNA and is complementary to the junction between the second and third genes of the sdh operon (sdhD and sdhA)
NrrF_RNA
Protein-coding gene in the species Homo sapiens
the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit. SDHD forms part of the transmembrane protein dimer with SDHC that
SDHD
Letter "Ḍha" in Indic scripts
(p) + ढ (ḍʱa) gives the ligature pḍʱa: ष্ (ṣ) + ढ (ḍʱa) gives the ligature ṣḍʱa: Vertically stacked ligatures are the most common conjunct forms found in
Ḍha
RNA family
genomics approach was able to detect and verify the additional targets ptsI, sdhA and yobF. RydB RNA RyhB RNA RyeB RNA Wassarman, KM; Repoila F; Rosenow C;
RyeE_RNA
Protein-coding gene in the species Homo sapiens
that make up the succinate dehydrogenase heterotetrmer, i.e., the SDHD, SDHA, SDHC, and SDHB genes (inactivation of any one of these genes causes paraganglioma
SUCNR1
Q99470 14437 SDF2L1 HGNC:10676; Q9HCN8 14438 SDF4 HGNC:24188; Q9BRK5 14439 SDHA HGNC:10680; P31040 14440 SDHAF1 HGNC:33867; A6NFY7 14441 SDHAF2 HGNC:26034;
List of human protein-coding genes 7
List_of_human_protein-coding_genes_7
Chemical compound
(2017). "Cloning and functional analysis of succinate dehydrogenase gene PsSDHA in Phytophthora sojae". Microbial Pathogenesis. 108: 40–48. doi:10.1016/j
3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic_acid
Cardiomyopathy, dilated, 1G; 604145; TTN Cardiomyopathy, dilated, 1GG; 613642; SDHA Cardiomyopathy, dilated, 1I; 604765; DES Cardiomyopathy, dilated, 1J; 605362;
List_of_OMIM_disorder_codes
Protein-coding gene in the species Homo sapiens
proteins (IDH3A, IDH2, SUCLG2, DLST); Respiratory chain proteins (NDUFS1, SDHA, ATP5F1A, ETFA, ETFB); Mitochondrial RNA processing proteins (LRPPRC, DHX30
FASTKD3
RNA family
dependent expression of the IscR regulon. Further targets of FnrS are nagZ and sdhA. There is also evidence to suggest that the expression of FnrS is regulated
FnrS_RNA
SDHA
SDHA
SDHA
SDHA
Girl/Female
Hindu, Indian, Marathi, Tamil
Birth Place of Lord Krishna; A Bird; The Place of the Ancient Kingdoms
Boy/Male
Gujarati, Hindu, Indian, Kannada
Sun
Female
Basque
, a fairy, genius, peri; ("sympathetic").
Girl/Female
Arabic, Muslim
Star
Girl/Female
Arabic, Muslim
Confident; Sure; Certain; Feminine of Wasiq
Girl/Female
Tamil
Attainment, Achievement, A bird
Boy/Male
Hindu
Reviver of lakshmanas life
Boy/Male
Arabic, Muslim
Servant of the Forgiver
Male
English
English surname transferred to forename use, derived from Old English Godwin, GOODWIN means "God's friend."
Boy/Male
Arabic, Muslim
Brightness; Light
SDHA
SDHA
SDHA
SDHA
SDHA