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SALUTARIDINE

Salutaridine

Chemical compound

Salutaridine, also known as floripavine, is an alkaloid that is present in the morphinan alkaloid pathway of opium poppy, Papaver somniferum. It is produced

Salutaridine

Reticuline

Chemical compound

magnoflorine Salutaridine synthase uses (R)-reticuline, NADPH, and oxygen to produce salutaridine. (R)-reticuline + NADPH O2 2 H2O salutaridine + NADP+

Reticuline

Salutaridine reductase (NADPH)

Enzyme

In enzymology, salutaridine reductase (NADPH) (EC 1.1.1.248) is an enzyme that catalyzes the chemical reaction salutaridine + NADPH H+ salutaridinol

Salutaridine reductase (NADPH)

Salutaridine_reductase_(NADPH)

Morphine

Pain medication of the opiate family

converted into salutaridine, thebaine, and oripavine. The enzymes involved in this process are the salutaridine synthase, salutaridine:NADPH 7-oxidoreductase

Morphine

Salutaridine synthase

Class of enzymes

enzymology, salutaridine synthase (EC 1.14.19.67) is an enzyme that catalyzes the chemical reaction (R)-reticuline + NADPH O2 2 H2O salutaridine + NADP+

Salutaridine synthase

Salutaridine_synthase

Salutaridinol

Chemical compound

pathway of secondary metabolism. Salutaridinol is a product of the enzyme salutaridine: NADPH 7-oxidoreductase and the substrate for the enzyme salutaridinol

Salutaridinol

1,2-dehydroreticuline synthase

Class of enzymes

(S)-reticuline is converted to {R)-reticuline, which is the precursor of salutaridine, on the pathway to morphine. This gene fusion event has been suggested

1,2-dehydroreticuline synthase

1,2-dehydroreticuline_synthase

List of EC numbers (EC 1)

Now EC 1.14.21.3, berbamunine synthase EC 1.1.3.35: Now EC 1.14.21.4, salutaridine synthase EC 1.1.3.36: Now EC 1.14.21.5, (S)-canadine synthase EC 1.1

List of EC numbers (EC 1)

List_of_EC_numbers_(EC_1)

C19H21NO4

Index of chemical compounds with the same molecular formula

(isoboldine) 3-Monoacetylmorphine 6-Monoacetylmorphine Naloxone (+)-Naloxone Salutaridine Scoulerine Stepholidine This set index page lists chemical structure

C19H21NO4

1,2-dehydroreticulinium reductase (NADPH)

Class of enzymes

reticuline is converted to {R)-reticuline, which is the precursor of salutaridine, on the pathway to morphine. This gene fusion event has been suggested

1,2-dehydroreticulinium reductase (NADPH)

1,2-dehydroreticulinium_reductase_(NADPH)

Phenol oxidation with hypervalent iodine reagents

reaction has been employed to transform reticuline derivatives into salutaridine derivatives in a single, presumably biomimetic, step. Yields of reactions

Phenol oxidation with hypervalent iodine reagents

Phenol_oxidation_with_hypervalent_iodine_reagents

Alan R. Battersby

English organic chemist (1925–2018)

biosynthesis of morphine was shown to proceed from L-tyrosine via reticuline, salutaridine, thebaine, codeinone and codeine. The Battersby group worked on many

Alan R. Battersby