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MLL4

  • KMT2D
  • Protein-coding gene in humans

    Histone-lysine N-methyltransferase 2D (KMT2D), also known as MLL4 and sometimes MLL2 in humans and Mll4 in mice, is a major mammalian histone H3 lysine 4 (H3K4)

    KMT2D

    KMT2D

    KMT2D

  • MLL4
  • Protein-coding gene in the species Homo sapiens

    Myeloid/lymphoid or mixed-lineage leukemia 4, also known as MLL4, is a human gene. This gene encodes a protein which contains multiple domains including

    MLL4

    MLL4

    MLL4

  • H3K4me1
  • Histone methylation on tail of histone H3 associated with enhancers

    identity. Enhancers are primed by histone H3K4 mono-/di-methyltransferase MLL4 and then are activated by histone H3K27 acetyltransferase p300. H3K4me1 fine-tunes

    H3K4me1

    H3K4me1

  • Lysine-specific demethylase 6A
  • Protein-coding gene in humans

    Cho YW, Hong T, Hong S, et al. (2007). "PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex". J. Biol. Chem

    Lysine-specific demethylase 6A

    Lysine-specific demethylase 6A

    Lysine-specific_demethylase_6A

  • SOX9
  • Transcription factor gene of the SOX family

    shown to interact with steroidogenic factor 1, MED12, MAF, SWI/SNF, MLL3 and MLL4. Loss of function mutations with Sox9 can lead to campomelic dysplasia (CD)

    SOX9

    SOX9

    SOX9

  • HOXC10
  • Protein-coding gene in the species Homo sapiens

    transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4. Methylation of the estrogen-repressed gene HOXC10 in breast cancer determines

    HOXC10

    HOXC10

    HOXC10

  • Histone methyltransferase
  • Class of enzymes

    activity include: ASH1L DOT1L EHMT1, EHMT2, EZH1, EZH2 MLL, MLL2, MLL3, MLL4, MLL5 NSD1 PRDM2 SET, SETBP1, SETD1A, SETD1B, SETD2, SETD3, SETD4, SETD5

    Histone methyltransferase

    Histone methyltransferase

    Histone_methyltransferase

  • Pioneer factor
  • Transcription factor

    of DNA methylation. SOX9 recruits histone modification enzymes MLL3 and MLL4 to deposit H3K4me1 prior to the opening of enhancers in developing hair follicle

    Pioneer factor

    Pioneer_factor

  • PAXIP1
  • Protein-coding gene in the species Homo sapiens

    GR, Copeland TD, Kalkum M, Ge K (2007). "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex". J. Biol. Chem

    PAXIP1

    PAXIP1

    PAXIP1

  • KMT2C
  • Protein-coding gene in the species Homo sapiens

    Guo H, Yu H, Kim D, et al. (July 2007). "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex". The Journal of

    KMT2C

    KMT2C

    KMT2C

  • C19Orf81
  • Human protein and gene

    cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4). Human molecular genetics, 31(21), 3715–3728. https://doi.org/10.1093/hmg/ddac121

    C19Orf81

    C19Orf81

    C19Orf81

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Online names & meanings

  • HEADLEY
  • Male

    English

    HEADLEY

    Variant spelling of English Hedley, HEADLEY means "heather field."

  • Sankith
  • Boy/Male

    Hindu

    Sankith

  • Sigrath
  • Girl/Female

    Norse

    Sigrath

    Conquering advisor.

  • Takseen
  • Girl/Female

    Arabic

    Takseen

    Satisfaction; Peace

  • Nuhaa
  • Girl/Female

    Muslim/Islamic

    Nuhaa

    Intelligent

  • Winthrop
  • Boy/Male

    English Teutonic

    Winthrop

    Friend's village; friend's farm; from Wine's estate.

  • Ahkaf
  • Boy/Male

    Arabic

    Ahkaf

    Gift from All the Gods

  • Abhinu | அபிநுஂ
  • Boy/Male

    Tamil

    Abhinu | அபிநுஂ

    Brave Man

  • Bodhidharma
  • Boy/Male

    Buddhist, Indian, Sanskrit

    Bodhidharma

    All-pervading Enlightened Mind; Enlightenment Teaching

  • Shallum
  • Boy/Male

    Australian, Biblical, Christian, Hebrew

    Shallum

    Perfect; Agreeable; Retribution

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