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MBD3

  • MBD3
  • Protein-coding gene in the species Homo sapiens

    Methyl-CpG-binding domain protein 3 is a protein that in humans is encoded by the MBD3 gene. DNA methylation is the major modification of eukaryotic genomes and

    MBD3

    MBD3

    MBD3

  • Methyl-CpG-binding domain protein 2
  • Protein-coding gene in the species Homo sapiens

    essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in

    Methyl-CpG-binding domain protein 2

    Methyl-CpG-binding domain protein 2

    Methyl-CpG-binding_domain_protein_2

  • Methyl-CpG-binding domain
  • Protein family

    cases of MeCP2, MBD1 and MBD2, preferentially to methylated CpG. In human MBD3 and SETDB1, the MBD has been shown to mediate protein-protein interactions

    Methyl-CpG-binding domain

    Methyl-CpG-binding domain

    Methyl-CpG-binding_domain

  • Jacob Hanna
  • Israeli Arab researcher in molecular biochemistry

    efficiencies (up to 100% within 8 days) via optimized depletion of Gatad2a/Mbd3 core member-axis of the NuRD co-repressor complex. The latter work set the

    Jacob Hanna

    Jacob Hanna

    Jacob_Hanna

  • Induced pluripotent stem cell
  • Pluripotent stem cell generated directly from a somatic cell

    deacetylation (NuRD) complex. Overexpression of Mbd3, a subunit of NuRD, inhibits induction of iPSCs. Depletion of Mbd3, on the other hand, improves reprogramming

    Induced pluripotent stem cell

    Induced pluripotent stem cell

    Induced_pluripotent_stem_cell

  • List of human transcription factors
  • ENSG00000134046 MBD Known motif – In vivo/Misc source [510] VSGKCCGGMKR MBD3 ENSG00000071655 MBD Likely sequence specific TF according to literature or

    List of human transcription factors

    List_of_human_transcription_factors

  • Aurora kinase A
  • Protein-coding gene in the species Homo sapiens

    drug resistant tumors. Aurora A kinase has been shown to interact with: MBD3, MYCN, NME1, P53, TACC1, TPX2, and UBE2N. GRCh38: Ensembl release 89: ENSG00000087586

    Aurora kinase A

    Aurora kinase A

    Aurora_kinase_A

  • Mi-2/NuRD complex
  • Protein complex

    metastasis-associated proteins MTA1 (or MTA2 / MTA3), the methyl-CpG-binding domain protein MBD3 (or MBD2) and the chromodomain-helicase-DNA-binding protein CHD3 (aka Mi-2alpha)

    Mi-2/NuRD complex

    Mi-2/NuRD_complex

  • MBD4
  • Protein-coding gene in the species Homo sapiens

    essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 (this gene) comprise a family of nuclear proteins related by the

    MBD4

    MBD4

    MBD4

  • HDAC1
  • Protein-coding gene in the species Homo sapiens

    deacetylase 2, Homeobox protein TGIF1, Host cell factor C1, IFRD1, IKZF1, ING1, MBD3, MIER1, MLL, MTA1, MTA2, Mad1, Mdm2, Methyl-CpG-binding domain protein 2

    HDAC1

    HDAC1

    HDAC1

  • MTA2
  • Protein-coding gene in the species Homo sapiens

    CLOCK-BMAL1 complex. MTA2 has been shown to interact with: CHD4, HDAC1, HDAC2, MBD3 MTA1, RBBP4, RBBP7, and SATB1. GRCh38: Ensembl release 89: ENSG00000149480

    MTA2

    MTA2

    MTA2

  • MBD1
  • Protein-coding gene in the species Homo sapiens

    essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in

    MBD1

    MBD1

    MBD1

  • GATAD2B
  • Protein-coding gene in the species Homo sapiens

    GATAD2B has been shown to interact with Methyl-CpG-binding domain protein 2, MBD3, RBBP7 and RBBP4. ENSG00000261992 GRCh38: Ensembl release 89: ENSG00000143614

    GATAD2B

    GATAD2B

    GATAD2B

  • List of human protein-coding genes 5
  • HGNC:30438; Q8IYB1 9307 MBD1 HGNC:6916; Q9UIS9 9308 MBD2 HGNC:6917; Q9UBB5 9309 MBD3 HGNC:6918; O95983 9310 MBD3L1 HGNC:15774; Q8WWY6 9311 MBD3L2 HGNC:18532;

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • DNMT1
  • Protein-coding gene in the species Homo sapiens

    PMID 10753866. Tatematsu KI, Yamazaki T, Ishikawa F (August 2000). "MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1

    DNMT1

    DNMT1

    DNMT1

  • CHD4
  • Protein-coding gene in humans

    Saito M, Ishikawa F (September 2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"

    CHD4

    CHD4

    CHD4

  • SALL4
  • Protein-coding gene in the species Homo sapiens

    metastasis-associated proteins (MTA), methyl-CpG-binding domain proteins (MBD2 or MBD3), and histone deacetylases (HDAC1 and HDAC2). This association allows SALL4

    SALL4

    SALL4

    SALL4

  • Histone deacetylase 2
  • Protein-coding gene in the species Homo sapiens

    new family of potent transcriptional repressors interacting with MBD2 and MBD3". The Journal of Biological Chemistry. 277 (43): 40958–40966. doi:10.1074/jbc

    Histone deacetylase 2

    Histone deacetylase 2

    Histone_deacetylase_2

  • SAP30
  • Protein-coding gene in the species Homo sapiens

    Saito M, Ishikawa F (September 2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"

    SAP30

    SAP30

    SAP30

  • RBBP7
  • Protein-coding gene in the species Homo sapiens

    PMID 11788710. Saito M, Ishikawa F (2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"

    RBBP7

    RBBP7

    RBBP7

  • Dipeptidase 3
  • Protein-coding gene in the species Homo sapiens

    DPEP3 Identifiers Aliases DPEP3, MBD3, dipeptidase 3 External IDs OMIM: 609926; MGI: 1919104; HomoloGene: 23357; GeneCards: DPEP3; OMA:DPEP3 - orthologs

    Dipeptidase 3

    Dipeptidase 3

    Dipeptidase_3

  • EIF3A
  • Protein-coding gene in the species Homo sapiens

    PMID 11384103. Saito M, Ishikawa F (2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"

    EIF3A

    EIF3A

    EIF3A

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Online names & meanings

  • Abja | அப்ஜா
  • Girl/Female

    Tamil

    Abja | அப்ஜா

    Born in water

  • Mubid |
  • Boy/Male

    Muslim

    Mubid |

    Intellectual

  • Atrim
  • Boy/Male

    Hindu, Indian

    Atrim

    Earth

  • OGRUFENA
  • Female

    Russian

    OGRUFENA

    Variant form of Russian Agrafina, OGRUFENA means "wild horse."

  • Eliza
  • Girl/Female

    Indian

    Eliza

    Unique, Precious

  • Raspberry
  • Surname or Lastname

    English

    Raspberry

    English : variant spelling of Rasberry.

  • Durrell
  • Boy/Male

    American, British, English

    Durrell

    King's Doorkeeper; Strong

  • Atikah
  • Girl/Female

    Arabic, Malaysian, Muslim

    Atikah

    Clear; Virgin; Pure; Clean

  • ZUBIN
  • Male

    English

    ZUBIN

     English name of Russian origin, ZUBIN means "toothy." Compare with other forms of Zubin.

  • Aeyush
  • Boy/Male

    Indian

    Aeyush

    Long lived

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MBD3

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