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FOXD3

  • FOXD3
  • Protein-coding gene in the species Homo sapiens

    Forkhead box D3 also known as FOXD3 is a forkhead protein that in humans is encoded by the FOXD3 gene. This gene belongs to the forkhead protein family

    FOXD3

    FOXD3

    FOXD3

  • Neural crest
  • Pluripotent embryonic cell group giving rise to diverse cell lineages

    sufficient for the expression of Slug, Snail, and FoxD3. Furthermore, Pax3 is essential for FoxD3 expression in mouse embryos. Following the expression

    Neural crest

    Neural crest

    Neural_crest

  • Pioneer factor
  • Transcription factor

    cell types and has to be removed only when cell differentiation begins. FoxD3 has been associated as a repressor of both B-cell and melanocytic cell differentiation

    Pioneer factor

    Pioneer_factor

  • Neuronal lineage marker
  • Endogenous tag expressed in different cells along neurogenesis and differentiated cells

    FABP7/B-FABP; PKC zeta; FABP 8/M-FABP; Prominin-2; FGFR2; ROR2; FGFR4; RUNX1/CBFA2; FoxD3; RXR alpha/NR2B1; Frizzled-9; sFRP-2; GATA-2; SLAIN 1; GCNF/NR6A1; SOX1;

    Neuronal lineage marker

    Neuronal lineage marker

    Neuronal_lineage_marker

  • Marianne Bronner
  • Developmental biologist

    Bronner, M.E. (2012) Dynamic and differential regulation of stem cell factor FoxD3 in the neural crest is encrypted in the genome PLoS. Genetics e1003142.

    Marianne Bronner

    Marianne Bronner

    Marianne_Bronner

  • List of human transcription factors
  • ENSG00000186564 Forkhead Known motif – High-throughput in vitro [247] RTAAAYA FOXD3 ENSG00000187140 Forkhead Known motif – High-throughput in vitro [248] RTAAAYA

    List of human transcription factors

    List_of_human_transcription_factors

  • FOXD4L6
  • Human gene

    ten subfamilies (FOXA–FOXS). The FOXD sub class includes FOXD1, FOXD2, FOXD3, and the FOXD4/FOXD4-like expansion present in primates. In humans, this

    FOXD4L6

    FOXD4L6

    FOXD4L6

  • FOX proteins
  • Family of transcription factors involved in anatomical development

    FOXC1 (associated with glaucoma), FOXC2 (varicose veins) FOXD1, FOXD2, FOXD3 (vitiligo), FOXD4, FOXD4L1, FOXD4L3, FOXD4L4, FOXD4L5, FOXD4L6 FOXE1 (thyroid)

    FOX proteins

    FOX proteins

    FOX_proteins

  • Oct-4
  • Mammalian protein found in Homo sapiens

    (March 2002). "The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression". Proceedings

    Oct-4

    Oct-4

    Oct-4

  • Morpholino nucleic acid
  • Chemical compound

    Johnson RL, Erickson CA (April 2001). "The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis

    Morpholino nucleic acid

    Morpholino nucleic acid

    Morpholino_nucleic_acid

  • Evolution of schizophrenia
  • Theory of natural selection

    disorganized speech. A study published in 2017 targeted various candidate genes (FOXD3, RET, SOX9, SOX10, GDNF) with overlapping function in relation to schizophrenia

    Evolution of schizophrenia

    Evolution_of_schizophrenia

  • PRDM12
  • Protein-coding gene in the species Homo sapiens

    regions" of the SIX1, PAX3, ISLET1, and PAX6 genes, but not those of the FOXD3 and SIX3 genes. In cases where BMP4 was overexpressed, embryos showed an

    PRDM12

    PRDM12

    PRDM12

  • WNT8A
  • Protein-coding gene in the species Homo sapiens

    various other genes important for neural crest induction (pax3, sox10, and foxd3). It is unclear however, if the loss of these neural crest specifiers is

    WNT8A

    WNT8A

    WNT8A

  • SNAI2
  • Protein

    differentiation and migration of neural crest cells along with other genes (e.g. FOXD3, SOX9 and SOX10, BMPs) in embryonic life. Mutations in this gene may be

    SNAI2

    SNAI2

    SNAI2

  • SOX10
  • Transcription factor gene of the SOX family

    neurons. Other cofactors have been identified, such as SP1, OCT6, NMI, FOXD3 and SOX2. The interaction between SOX10 and NMI seems to be coexpressed

    SOX10

    SOX10

    SOX10

  • TMEM202
  • anterior-posterior axis. SNP rs74343303, 193 bases upstream also interferes with FOXD3 binding. FOXD3 has the ability to act as a transcriptional activator and repressor

    TMEM202

    TMEM202

    TMEM202

  • List of human protein-coding genes 3
  • HGNC:3801; Q99958 5794 FOXD1 HGNC:3802; Q16676 5795 FOXD2 HGNC:3803; O60548 5796 FOXD3 HGNC:3804; Q9UJU5 5797 FOXD4 HGNC:3805; Q12950 5798 FOXD4L1 HGNC:18521;

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • Neurula
  • Embryo at the early stage of development in which neurulation occurs

    in the lack of activation of the specific neural crest genes Snail2 and Foxd3, which didn't allow further development or emigration of neural crest. Using

    Neurula

    Neurula

    Neurula

  • Cingulin
  • Protein found in humans

    Johnson RL, Erickson CA (April 2001). "The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis

    Cingulin

    Cingulin

    Cingulin

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Online names & meanings

  • MIKAYLA
  • Female

    English

    MIKAYLA

    Variant spelling of English Michaela, MIKAYLA means "who is like God?"

  • Isshiah
  • Biblical

    Isshiah

    there is God;

  • Ishanika | இஷாநிகா
  • Girl/Female

    Tamil

    Ishanika | இஷாநிகா

    Fulfilling desire, Belonging to the north east

  • Domingos
  • Boy/Male

    Australian, British, English

    Domingos

    Lord; Belongs to the Lord

  • Vima
  • Girl/Female

    Hindu

    Vima

    Insurance

  • Rudrapratap
  • Boy/Male

    Hindu, Indian

    Rudrapratap

    Lord Shiva

  • Taqiyya
  • Girl/Female

    Arabic, Muslim

    Taqiyya

    Pious; Righteous

  • Avisri
  • Girl/Female

    Bengali, Hindu, Indian

    Avisri

    Beauty

  • Bentleigh
  • Girl/Female

    British, English

    Bentleigh

    Meadow of Grass

  • JEFFERY
  • Male

    English

    JEFFERY

    Variant spelling of English Jefferey, probably JEFFERY means "God's peace." 

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