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Chain molecule which folds in predictable ways while in solution
In chemistry, a foldamer is a discrete chain molecule (oligomer) that folds into a conformationally ordered state in solution. They are artificial molecules
Foldamer
British organic chemist and professor at Bristol
atropisomerism, organolithium chemistry, remote stereochemical effects and dynamic foldamer chemistry. He is one of the authors of the organic chemistry textbook -
Jonathan_Clayden
How a molecule assumes its conformation
deal of interest in the construction of artificial folding molecules or foldamers. They are studied as models of biological molecules and for potential
Folding_(chemistry)
Branch of chemistry
p-xylylenediammonium bound within a cucurbituril Intramolecular self-assembly of a foldamer Two pyrene butyric acids bound within a C-hexylpyrogallol[4]arenes nanocapsule
Supramolecular_chemistry
French chemist, Nobel laureate (born 1939)
Crystal structure of a foldamer reported by Lehn et al. in Helv. Chim. Acta., 2003, 86, 1598–1624.
Jean-Marie_Lehn
American biochemist
molecules that nature did not synthesize—miniature proteins, β-peptide foldamers, polyproline hairpins, and proto-fluorescent ligands—and the use of these
Alanna_Schepartz
Possible alternative biochemicals used by life forms
Glycine, or Ornithine as the basic structure for protein-like polymers (foldamers) would lead to parallel biological worlds. They would have morphologically
Hypothetical types of biochemistry
Hypothetical_types_of_biochemistry
Class of peptides derived from β-amino acids
Christianson LA, Karle IL, Powell DR, Gellman SH (1996). "β-Peptide Foldamers: Robust Helix Formation in a New Family of -Amino Acid Oligomers". J.
Beta-peptide
Protein structural motif
between polar/watery and nonpolar/greasy environments. Collagen helix Foldamers Folding (chemistry) Tertiary structure α-helix Structural motif "Animated
Beta_sheet
Organic chemistry effect
example of this is an olefin metathesis reaction: In the field of peptide foldamers, amino acid residues containing quaternary carbons such as 2-aminoisobutyric
Thorpe–Ingold_effect
Science of synthetic life forms
Biological dark matter Body plan Directed evolution Expanded genetic code Foldamer Hachimoji DNA Hypothetical types of biochemistry Life definitions Nucleic
Xenobiology
Movement of molecules into a defined arrangement without outside influence
form of 2D crystal engineering at the nanoscopic scale. Assembly theory Foldamer Ice-nine Macromolecular assembly Self-assembly of nanoparticles Supramolecular
Molecular_self-assembly
Croatian chemist
Vladimir Kubyshkin, the new-to-nature hydrophobic polyproline-II helix foldamer was designed. Along with Budisa's previous work on bioexpression using
Nediljko_Budisa
Interactions between nucleic acid modules
PMID 843604. S2CID 35930758. Chworos A, Jaeger, Luc (2007). "Nucleic acid foldamers: design, engineering and selection of programmable biomaterials with recognition
Nucleic acid quaternary structure
Nucleic_acid_quaternary_structure
Class of compounds designed to mimic features of peptides
particular peptide binding motif. Examples involve D-peptide and peptidic foldamers such as beta-peptides. These structural mimetics include molecules that
Peptidomimetic
Molecules that mimic protein characteristics
Cabalteja CC, Mihalko DS, Horne WS (November 2018). "Heterogeneous-backbone foldamer mimics of a computationally designed, disulfide-rich miniprotein". ChemBioChem
Proteomimetic
Chemical compound
the market. Brilacidin, a non-peptide chemical mimic, is an aryl amide foldamer designed to replicate the amphiphilic properties of antimicrobial peptides
Brilacidin
Polymeric arrays of repeating units connected by non-covalent bonds
"Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions". Chemical
Supramolecular_polymer
Classification of membrane proteins including ion channels
24 The Marine Sponge Polytheonamide B (pTB) Family 1.D.25 The Arylamine Foldamer (AAF) Family 1.D.26 The Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside
Transporter Classification Database
Transporter_Classification_Database
Peptides that facilitate cellular intake
chain has multiple advantages. It facilitates the formation of stable foldamers with distinct secondary structure. β-Peptides are conformationally more
Cell-penetrating_peptide
Optical phenomenon
was replicated in organic molecules, specifically aromatic oligoamide foldamers. Whereas the initial experimental demonstration of hyper-Rayleigh scattering
Hyper–Rayleigh_scattering
German chemist (born 1974)
Christian; Hecht, Stefan (13 March 2006). "Prototype of a Photoswitchable Foldamer". Angewandte Chemie International Edition. 45 (12): 1878–1881. Bibcode:2006ACIE
Stefan_Hecht
American chemist
macromolecular architectures, the molecular construction of structures such as foldamers, and the synthesis of shape-persistent macrocycles. Understanding the
Jeffrey_S._Moore
Polymers of N-substituted glycines
heterogeneity which doesn’t allow for the formation of homogeneous peptoid foldamers. Nonetheless, scientists were able to find trans-inducer N-Aryl side chains
Peptoid
Chemical compound
been created, including fibrillar gels, micelles, vesicles, nanotubes, foldamers and liquid crystalline phases. In analogy to biological systems, which
Cyclobis(paraquat-p-phenylene)
Cyclobis(paraquat-p-phenylene)
molecular modelling. His major researches include synthesis of peptides, foldamers and proteins by solid state synthesis and biotechnological methods. He
András_Perczel
Dutch systems chemistry professor
nanoparticle surfaces). Specific interests include self-replicating molecules, foldamers, catalysis, molecular recognition of biomolecules and self-synthesizing
Sijbren_Otto
Indian bio organic chemist
researches on the synthesis of designer peptide/protein mimetics and hetero-foldamers and is a recipient of the Bronze Medal of the Chemical Research Society
Gangadhar_J._Sanjayan
aren't easily accessible by other means. These include smart materials, foldamers, self-assembling molecules with interlocking architectures and new soft
Dynamic combinatorial chemistry
Dynamic_combinatorial_chemistry
dynamics of photoisomerization and subsequent unfolding of an oligoazobenzene foldamer". J Am Chem Soc. 138 (39): 12997–13005. Bibcode:2016JAChS.13812997S. doi:10
Cluster of Excellence Frankfurt Macromolecular Complexes
Cluster_of_Excellence_Frankfurt_Macromolecular_Complexes
Martin V, Legrand B, Vezenkov LL. Turning peptide sequences into ribbon foldamers by a straightforward multicyclization reaction. Angewandte Chemie 2015;54:1-6
Beta_bend_ribbon
principles it was easily extended to design biologically active polymers and foldamers (short homogeneous, sequence-specific polymers that fold into unique structures)
William_DeGrado
Type of protein
and non-native peptides: using Affimers to recognise α-helix mimicking foldamers" (PDF). Chemical Communications. 53 (19): 2834–2837. doi:10.1039/c6cc09395g
Affimer
FOLDAMER
FOLDAMER
FOLDAMER
FOLDAMER
Surname or Lastname
English (Oxfordshire)
English (Oxfordshire) : from the personal name Pipkin, a pet form of Philip.
Girl/Female
Tamil
Yogamaya | யோகமாயா
The Maya directly in touch with the God
Girl/Female
Arabic, Egyptian, French, Muslim
To Collect; To Rest; Married to the Prophet; Wife of Prophet Muhammad; Gathering; Brave
Female
Italian
Italian form of Greek Philomena, FILUMENA means "friend of ease."
Boy/Male
Hindu, Indian, Mythological
Shiva's Son
Girl/Female
Indian
Wife.
Male
Italian
Short form of Italian/Spanish Anacleto, CLETO means "called back, invoked."
Girl/Female
Indian
Initiation
Girl/Female
Arthurian Legend
Wife of Percival.
Boy/Male
Muslim/Islamic
Highland
FOLDAMER
FOLDAMER
FOLDAMER
FOLDAMER
FOLDAMER