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Search references for DIRECT BINDING. Phrases containing DIRECT BINDING
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Feature of linker and dynamic linker on Solaris
Direct binding is a feature of the linker and dynamic linker on Solaris and OpenSolaris. It provides a method to allow libraries to directly bind symbols
Direct_binding
Property of hemoglobin and oxygenation
favours direct binding of CO2 to Hb amino acid residues to form carbamino compounds (the more significant component), as well as the binding of H+ ions
Haldane_effect
Peptide encoded in mitochondrial DNA
Hemal H; Yen, Kelvin; Cohen, Pinchas (May 2023). "Casein kinase 2 is a direct binding partner and a functional target of the exercise-mimetic microprotein
MOTS-c
Human glycoprotein that binds to androgens and estrogens
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens. When produced by the
Sex_hormone–binding_globulin
Former Chinese custom
Foot binding (simplified Chinese: 缠足; traditional Chinese: 纏足; pinyin: chánzú), or footbinding, was the Chinese custom of breaking and tightly binding the
Foot_binding
Level of opacity to the radio wave and X-ray portion of the electromagnetic spectrum
sulfate, bismuth oxide and zirconium oxide. Some solutions involve direct binding of heavy elements, for instance iodine, to polymeric chains in order
Radiodensity
Chemical compound
organization, polymerization, and branching of filamentous actin (F-actin) via direct binding to F-actin regulatory proteins. The first evidence that indicated
Phosphatidylinositol 4,5-bisphosphate
Phosphatidylinositol_4,5-bisphosphate
Species of virus affecting humans and animals
infection via its direct binding to the viral GP, and that it is the second "lysosomal" domain of NPC1 that mediates this binding. The second candidate
Zaire_ebolavirus
Direct vote on a specific proposal
is a direct vote by the electorate (rather than their representatives) on a proposal, law, or political issue. A referendum may be either binding, resulting
Referendum
Plant species in the bunchflower family
Taipale, J; Cooper, M. (2002). "Inhibition of Hedgehog Signaling by direct binding of Cyclopamine to Smoothened". Genes Dev. 16 (21): 2743–2748. doi:10
Veratrum_californicum
Protein
Binding causes a conformational change in the receptor which, depending on the class of receptor, triggers a cascade of downstream events that direct
Nuclear_receptor
Protein found in humans
1997). "Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments". The Journal of Cell Biology.
Tight_junction_protein_ZO-1
Protein-coding gene in the species Homo sapiens
Harakawa N, Roumiantsev S, Varticovski L, Van Etten RA (June 2004). "A direct binding site for Grb2 contributes to transformation and leukemogenesis by the
GRB2
residues, though themselves not involved in direct binding, cause conformational shifts that regulate binding of microtubule associated proteins (MAP and
Polyglutamylation
Substance that forms a complex with a biomolecule
protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results
Ligand_(biochemistry)
Group of anti-nuclear antibodies
by indirect binding to DNA or nucleosomes that are adhered to the glomerular basement membrane (GBM). Another mechanism is direct binding of antibodies
Anti-dsDNA_antibodies
Medical blood test to measure transferrin
is less expensive than a direct measurement of transferrin. The TIBC should not be confused with the unsaturated iron-binding capacity or UIBC (LOINC 2501-5
Total_iron-binding_capacity
Drug discovery
multiple binding is thermodynamically advantageous and leads to sub-nanomolar inhibition (Ki = 0.3–0.6 nM). DX-9065a, the first small molecule direct Xa-inhibitor
Discovery and development of direct Xa inhibitors
Discovery_and_development_of_direct_Xa_inhibitors
Mechanism by which a computer program can load a library (or other binary) into memory
Computer programming portal Compile and go system DLL Hell Direct binding Dynamic binding (computing) Dynamic dispatch Dynamic library Dynamic linker
Dynamic_loading
Protein-coding gene in the species Homo sapiens
factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins
IGFBP3
Bacteriological technique
nucleic-acid stains whose retention depends on cell-wall integrity rather than direct binding to mycolic acids. Mycobacterium are slow-growing rod-shaped bacilli
Ziehl–Neelsen_stain
How drugs induce reversible suppression of consciousness
non-exclusionary with direct protein binding. The most recent hypothesis postulates that ordered lipids in the plasma membrane contain a structured binding site for
Theories of general anaesthetic action
Theories_of_general_anaesthetic_action
Operating system feature that integrates dynamic libraries into a program at runtime
actually being used. Computer programming portal Direct binding DLL Hell Dynamic loading Late binding prelink Dynamic dead-code elimination Not to be confused
Dynamic_linker
Japanese stem cell biologist
"Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4". Cell. 86 (4): 589–98. doi:10.1016/s0092-8674(00)80132-4
Yoshiki_Sasai
Unanswered question in the study of consciousness
(cognitive) binding problem is the problem of how objects, background, and abstract or emotional features are combined into a single experience. The binding problem
Binding_problem
Program that combines intermediate build files into an executable file
library (libbfd) Build (computing) Compile and go system DLL hell Direct binding Dynamic binding Dynamic dead-code elimination Dynamic dispatch Dynamic library
Linker_(computing)
Protein of the immune system
Heemels MT, Neefjes JJ, Kast W, Melief CJ, Ploegh HL (August 1990). "Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro"
MHC_class_I
Enzyme inhibition
already bound the substrate. This is unlike competitive inhibition, where binding affinity for the substrate in the enzyme is decreased in the presence of
Non-competitive_inhibition
Androgen and anabolic steroid
and water retention. It has been suggested that this may be due to direct binding to and activation of the estrogen receptor by oxymetholone. Oxymetholone
Oxymetholone
Protein domain
Harakawa N, Roumiantsev S, Varticovski L, Van Etten RA (June 2004). "A direct binding site for Grb2 contributes to transformation and leukemogenesis by the
BCR_(gene)
Immunity strategy in living beings
complement alternative pathway by Listeria monocytogenes: evidence for direct binding and proteolysis of the C3 component on bacteria". Infection and Immunity
Innate_immune_system
Part of an operating system
portal Application launcher Bug compatibility Compile and go system Direct binding DLL hell Dynamic-link library Dynamic dead-code elimination Dynamic
Loader_(computing)
Microbial protein found in Streptococcus pyogenes M1 GAS
about gene regulation and gene stoichiometry to be answered. Beyond direct binding of dCas9 to transcriptionally sensitive positions of loci, dCas9 can
Cas9
Compound that induces a loss of consciousness
perturbation to membrane lipid clusters and activation of phospholipase D2; direct binding of anesthetics to purified reconstituted TREK-1 had no effect on conductance
General_anaesthetic
Mammalian protein found in Homo sapiens
AV, Pierce KL, Daniel KW, Dixon TM, Lefkowitz RJ, Collins S (2000). "Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for
Beta-3_adrenergic_receptor
Restriction enzyme
and Asn116 (direct binding). Hydrogen bonding between water and Asn116 results in binding at A:T base pairs inside (water-mediated binding). As discussed
BamHI
Protein-coding gene in the species Homo sapiens
segments). Subsequently, direct binding to telomeric DNA was demonstrated through a co-crystal structure of the DNA-binding domain of HMBOX1 with telomeric
HMBOX1
Incapacitant spray similar to pepper spray
minutes. Pharmacologically, like other capsaicinoids, PAVA works by direct binding to receptors (TRPV1) that normally produce the pain and sensation of
PAVA_spray
Region of a messenger RNA
Instead of building up a complex at the 5′ cap, the IRES allows for direct binding of the ribosomal complexes to the transcript to begin translation. The
Five prime untranslated region
Five_prime_untranslated_region
Protein-coding gene in humans
PMID 8041791. Ward AC, Monkhouse JL, Hamilton JA, Csar XF (November 1998). "Direct binding of Shc, Grb2, SHP-2 and p40 to the murine granulocyte colony-stimulating
PTPN11
Chemical substance that enables neurotransmission
directly or indirectly. Direct-binding agonists can be further characterized as full agonists, partial agonists, inverse agonists. Direct agonists act similar
Neurotransmitter
Protein-coding gene in humans
11.4741. PMID 8943374. Ding Y, Sumitran S, Holgersson J (May 1999). "Direct binding of purified HLA class I antigens by soluble NKG2/CD94 C-type lectins
KLRC2
Form of democracy
with other votes, the vote may be binding or simply advisory. Initiatives may be direct or indirect: with the direct initiative, a successful proposition
Direct_democracy
Type of mating fastener
"Binding Barrels and Screws". Catalog. McMaster-Carr. Retrieved 29 April 2020. "Book Screws - Female | Components Direct". www.components-direct.com
Sex_bolt
Model of electronic band structures of solids
In solid-state physics, the tight-binding model (or TB model) is an approach to the calculation of electronic band structure using an approximate set
Tight_binding
British software developer
contributed a lot of time to decreasing program load time. He created the direct binding, hashvals, and dynsort implementations for GNU Binutils and glibc. Most
Michael Meeks (software developer)
Michael_Meeks_(software_developer)
Protein-coding gene in humans
(June 2003). "ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165". Journal of Biological Chemistry. 278
ADAMTS1
Central nervous system stimulant
though direct binding to the serotonin transporter was not observed. A later study confirmed the d-threo-methylphenidate (dexmethylphenidate) binding to the
Methylphenidate
RNA family
different mechanism from the usual 5' cap-binding model. This alternate mechanism relies on the direct binding of the 40S ribosomal subunit by the internal
Hepatitis C virus internal ribosome entry site
Hepatitis_C_virus_internal_ribosome_entry_site
sodium-dependant bicarbonate (Na+/HCO3−) symporters in the cytoplasmic membrane) by binding to it during the dark hours to prevent rising levels of Na+ from growing
SbtB_protein
Nematode
(2002). "Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H". The Journal of Infectious Diseases. 185 (12): 1786–1793
Onchocerca_volvulus
Protein-coding gene in humans
Increased expression of DDX3X by HIF1A in hypoxia is initiated by the direct binding of HIF1A to the HIF1A response element, as verified with chromatin immunoprecipitation
DDX3X
Chemical compound
include direct binding to and activation of sex hormone receptors, direct inhibition of enzymes involved in steroidogenesis, and direct binding to and
Danazol
Human protein and coding gene
Tareen SU, Melville MW, Blakely CM, Katze MG (September 2002). "The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein
Protein_kinase_R
Protein-coding gene in Homo sapiens
transport in migration. Another neuronal role for NSF is indicated by its direct binding to the GluR2 subunit of AMPA type glutamate receptors (which detect
N-ethylmaleimide sensitive fusion protein
N-ethylmaleimide_sensitive_fusion_protein
Protein-coding gene in the species Homo sapiens
to positions 2-8 of mature miR-145. NEDD9-binding regions in the miR-145 locus would allow the direct binding of the NEDD9 3'UTR to the genomic region
NEDD9
Medical condition
heterogeneous, including RPS26 (the known DBA10 gene), TSR2 which encodes a direct binding partner of RPS26, and RPS28. The phenotype of DBA patients suggests
Diamond–Blackfan_anemia
Family of proteins
assembly or activity of retroviral pre-integration complexes through direct binding to the retroviral proteins p55 Gag and matrix, as well as to DNA. Furukawa
Barrier-to-autointegration factor
Barrier-to-autointegration_factor
Protein-coding gene in the species Homo sapiens
GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. GAB2 is a docking protein with a conserved
GAB2
Human protein
Kato J, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ (March 1993). "Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation
Cyclin-dependent_kinase_4
Tools for the analysis of biomolecules
inferring direct DNA binding from ChIP-seq data. CentriMo is based on the observation that the positional distribution of binding sites matching the direct-binding
MEME_suite
Mammalian protein found in Homo sapiens
transmembrane domain are thought to sense increased cholesterol levels (direct sterol binding to the SSD of HMG-CoA reductase has not been demonstrated). Lysine
HMG-CoA_reductase
Drug discovery
response. Indirect-acting analog causes agonistic effect but without a direct binding to the β-adrenergic receptor, for example, by promoting release of norepinephrine
Discovery and development of beta2 agonists
Discovery_and_development_of_beta2_agonists
Biochemical analysis procedure
A ligand binding assay (LBA) is an assay, or an analytic procedure, which relies on the binding of ligand molecules to receptors, antibodies or other macromolecules
Ligand_binding_assay
Mammalian protein found in Homo sapiens
PMID 1502153. Czekay RP, Kuemmel TA, Orlando RA, Farquhar MG (May 2001). "Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein
LRP1
function in osteogenesis. These activities may be modulated by its direct binding to decorin and biglycan, two members of a family of small leucine-rich
WNT1-inducible-signaling pathway protein 1
WNT1-inducible-signaling_pathway_protein_1
Protein-coding gene in the species Homo sapiens
elements or direct binding by other initiation factors such as eIF3d. In contexts where eIF4E is bypassed or inhibited, other cap-binding proteins such
EIF4E
Proteins activated by the hormone estrogen
suppressor kinase LKB1 coactivates ERα in the cell nucleus through direct binding, recruiting it to the promoter of ERα-responsive genes. LKB1's catalytic
Estrogen_receptor
Mammalian protein found in Homo sapiens
11.4741. PMID 8943374. Ding Y, Sumitran S, Holgersson J (May 1999). "Direct binding of purified HLA class I antigens by soluble NKG2/CD94 C-type lectins
KLRD1
Protein-coding gene in the species Homo sapiens
K, Guillier M, Leibovitch SA (Jun 2000). "Stabilization of MyoD by direct binding to p57(Kip2)". The Journal of Biological Chemistry. 275 (25): 18767–76
Cyclin-dependent kinase inhibitor 1C
Cyclin-dependent_kinase_inhibitor_1C
Protein-coding gene in the species Homo sapiens
Fe(II)/Fe(III) coordination sites and the reaction proceeds through the direct binding of myo-inositol followed by attack of the iron center by diatomic oxygen
Inositol_oxygenase
Protein-coding gene in the species Homo sapiens
MS, Lischetti T, Streicher W, Kragh Nielsen T, et al. (March 2013). "Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression"
BUB1B
Class of enzymes
cytoplasmic subunits of the NFAT1 transcription complex, operating through direct binding through a conserved N terminus. Translocation of the NFAT transcription
Calcineurin
Cellular process of protein synthesis
until the start codon. The ribosome can localize to the start site by direct binding, initiation factors, and/or ITAFs (IRES trans-acting factors) bypassing
Translation_(biology)
German manufacturer of 3D printers
March 2015. "voxeljet AG: EuroMold premiere: 3D printing with Phenolic-Direct-Binding". FinanzNachrichten.de. Retrieved 27 November 2015. "Ford Motor setzt
Voxeljet
Protein complex in bacteria responsible for cell division
and FtsW), and activates FtsA mediated recruitment of FtsQLB through direct binding of FtsA. However, while FtsA, FtsQLB, FtsI and FtsW are widely conserved
Divisome
Protein found in humans
require direct binding to β-catenin, but necessitate interactions with Axin. The researchers hypothesized that APC's many β-catenin binding sites increase
Adenomatous_polyposis_coli
Mammalian protein found in Homo sapiens
factor and can also direct chromatin remodelling through binding to a DNA motif known as the E-box. MyoD is known to have binding interactions with hundreds
MyoD
outside the seed region can also alter this binding efficacy. The miR-206 regulation of ERα through the direct binding of miR-206 in the ERα 3' UTR, is a good
MiR-206
Cell surface receptor found in humans
Sano H, Iwaki D, Kudo K, Konishi M, Takahashi H, et al. (July 2003). "Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation
Toll-like_receptor_2
Plant immune response to infection
death. HR can be activated in two main ways: directly and indirectly. Direct binding of the virulence factors to the NLRs can result in the activation of
Hypersensitive_response
Protein found in humans
been found to play a role in erythroid cell differentiation through direct binding with GATA-1. In hematopoietic cells, ZNF521 mRNA is widely expressed
Zinc_finger_protein_521
Type of procedural memory
of binding the initial stimulus directly to the response while bypassing the intervening layers of computation. The mechanism mediating this direct binding
Repetition_priming
Human protein-coding gene on chromosome 9
Kolibaba K, Bhat A, Oda T, Ohno S, Fanning S, et al. (January 1997). "Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation". Blood
ABL_(gene)
Protein-coding gene in the species Homo sapiens
Kolibaba K, Bhat A, Oda T, Ohno S, Fanning S, Druker BJ (January 1997). "Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation". Blood
CRKL
Protein involved in blood vessel growth
(June 2003). "ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165". J. Biol. Chem. 278 (26): 23656–23665
Vascular endothelial growth factor A
Vascular_endothelial_growth_factor_A
Protein-coding gene in humans
Katoh H, Negishi M (July 2003). "RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo". Nature. 424 (6947): 461–464. Bibcode:2003Natur
RAC1
Family of transcription factors
distinct, pocket protein independent manner. E2F-6 mediates repression by direct binding to polycomb-group proteins or via the formation of a large multimeric
E2F
Japanese style of consensual rope bondage
Kinbaku (Japanese: 緊縛; 'tight binding'), also called kinbaku-bi (緊縛美; 'the beauty of tight binding'), is a Japanese style of bondage or BDSM which involves
Japanese_bondage
Protein-coding gene in the species Homo sapiens
PMID 23713811. Choi HY, Park N, Na JB, Ko ES, Park JY, Yoo JC (2016). "Direct binding of Copine3 with Jab1 activates downstream ErbB2 signaling and motility
Copine_3
Protein-coding gene in humans
PMC 15167. PMID 9892664. Itoh M, Furuse M, Morita K, et al. (2000). "Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with
CLDN4
Protein-coding gene in humans
Y, Tomoda K, Tanaka T, Arata Y, Yoneda-Kato N, Kato J (Apr 2001). "Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of
CDKN1B
American embryologist
Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of Chordin to BMP-4. Cell 86, 589-598. Piccolo, S., Agius, E., Lu, B
Edward_De_Robertis
Protein-coding gene in the species Homo sapiens
1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033. Haren L, Merdes A (2002). "Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail
Nuclear mitotic apparatus protein 1
Nuclear_mitotic_apparatus_protein_1
Class of corticosteroids
independent of any effects on transcription and can only be due to direct binding of activated glucocorticoid receptor with other proteins or with mRNA
Glucocorticoid
Chemical compound
kavain and related kavalactones are still debated. Direct binding to the benzodiazepine/flumazenil binding site of the GABA-A receptor does not occur with
Kavain
Protein found in humans
Cen B, Yu Q, Guo J, Wu Y, Ling K, Cheng Z, Ma L, Pei G (March 2001). "Direct binding of beta-arrestins to two distinct intracellular domains of the delta
Arrestin_beta_2
Protein-coding gene in humans
1006/mgme.1998.2698. PMID 9682218. Fang G, Yu H, Kirschner MW (1998). "Direct binding of CDC20 protein family members activates the anaphase-promoting complex
CDC20
Protein-coding gene in the species Homo sapiens
12613/9243. PMID 9242628. Kirsch KH, Georgescu MM, Hanafusa H (Oct 1998). "Direct binding of p130(Cas) to the guanine nucleotide exchange factor C3G". The Journal
Embryonal fyn-associated substrate
Embryonal_fyn-associated_substrate
Protein found in humans
PMID 2391353. Kouklis PD, Hutton E, Fuchs E (1994). "Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins". J.
Desmoplakin
DIRECT BINDING
DIRECT BINDING
Boy/Male
German
People's Ruler
Girl/Female
Indian, Sikh
Faithful
Boy/Male
Hindu, Indian, Marathi
One who Directs; Leader
Boy/Male
Hindu, Indian, Marathi
One who Directs; Guide
Boy/Male
Tamil
One who directs, Guide
Boy/Male
Indian, Punjabi, Sikh
Hearty Traditions
Girl/Female
Greek Latin
Killed for abusing children.
Girl/Female
Indian, Sikh
Lion
Boy/Male
Hindu
Direct evidence
Boy/Male
English American German
Leader.
Male
French
French form of Latin Benedictus, BÉNÉDICT means "blessed."Â
Boy/Male
Dutch
Dutch forms of Theodoric.
Male
Turkish
Turkish name DIRENÇ means "resistance."
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi
Crown
Boy/Male
Tamil
Pratyaksh | பà¯à®°à®¤à¯à®¯à®•à¯à®·
Direct evidence
Pratyaksh | பà¯à®°à®¤à¯à®¯à®•à¯à®·
Girl/Female
Hindu, Indian, Malayalam, Marathi, Telugu
Direct; Lead
Boy/Male
American, Australian, British, Chinese, English, German
Ruler of the People; The People's Ruler
Girl/Female
Teutonic American German Latin
Directed.
Boy/Male
Indian, Punjabi, Sikh
One who Sings Glory of God
Girl/Female
Tamil
Direct, Lead
DIRECT BINDING
DIRECT BINDING
Boy/Male
French
Cheerful; pretty.
Boy/Male
Arabic
Desire; Object
Boy/Male
Tamil
Computer
Boy/Male
Scottish
Black stranger.
Boy/Male
Hindu, Indian, Marathi, Telugu
Written
Girl/Female
Arabic
Tranquil
Boy/Male
Anglo Saxon
Name of a king.
Boy/Male
Tamil
One with auspicious marks
Boy/Male
Arabic
Strong Men
Girl/Female
Muslim/Islamic
Praise
DIRECT BINDING
DIRECT BINDING
DIRECT BINDING
DIRECT BINDING
DIRECT BINDING
v. t.
To point out or show to (any one), as the direct or right course or way; to guide, as by pointing out the way; as, he directed me to the left-hand road.
v. t.
To determine the direction or course of; to cause to go on in a particular manner; to order in the way to a certain end; to regulate; to govern; as, to direct the affairs of a nation or the movements of an army.
a.
Straight; not crooked, oblique, or circuitous; leading by the short or shortest way to a point or end; as, a direct line; direct means.
n.
One who, or that which, directs; one who regulates, guides, or orders; a manager or superintendent.
a.
Directed upward; raised; uplifted.
n.
A part of a machine or instrument which directs its motion or action.
a.
Not reaching the end aimed at by the most plain and direct method; as, an indirect proof, demonstration, etc.
n.
Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment.
a.
Not direct; not straight or rectilinear; deviating from a direct line or course; circuitous; as, an indirect road.
v. t.
To direct.
adv.
In a direct manner; in a straight line or course.
a.
In the line of descent; not collateral; as, a descendant in the direct line.
imp. & p. p.
of Direct
v. t.
To point out to with authority; to instruct as a superior; to order; as, he directed them to go.
a.
Not resulting directly from an act or cause, but more or less remotely connected with or growing out of it; as, indirect results, damages, or claims.
n.
One who directs; a director.
v. t.
To put a direction or address upon; to mark with the name and residence of the person to whom anything is sent; to superscribe; as, to direct a letter.
a.
Indirect.
adv.
In a straightforward way; without anything intervening; not by secondary, but by direct, means.
v. t.
To arrange in a direct or straight line, as against a mark, or towards a goal; to point; to aim; as, to direct an arrow or a piece of ordnance.