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Mammalian protein found in Homo sapiens
1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene. This protein binds the cAMP response element, a DNA nucleotide sequence
CREB1
Type of inflammatory bowel disease
by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2". PLOS ONE. 8 (11) e77773. Bibcode:2013PLoSO...877773D. doi:10
Crohn's_disease
Class of proteins
photoentrainment in mammals. The following genes encode CREB or CREB-like proteins: CREB1 (CREB1) CREB2 renamed ATF4 (ATF4) CREB3 (CREB3) CREB5 (CREB5) CREB3L1 (CREB3L1)
CREB
Rare form of cancer
cells express the EWSR1-ATF1 fusion gene in a majority of cases or a EWSR1-CREB1, EWSR1-CREM, or EWSR1-DDIT3 fusion gene in a small subset of cases (see
Clear_cell_sarcoma
Mammalian protein found in humans
BRCA1, BRCA2, BRCC3, BRE, CEBPZ, CDC14A, Cdk1, CFLAR, CHEK1, CCNG1, CREBBP, CREB1, Cyclin H, CDK7, DNA-PKcs, E4F1, EFEMP2, EIF2AK2, ELL, EP300, ERCC6, GNL3
P53
Family of RNA-binding proteins
fibrous histiocytoma: The neoplastic cells in these tumors express a EWSR1-CREB1 fusion gene in most cases or a EWSR1-CREB, FUS-CREB, EWSR1-ATF1, FUS-ATF1
FET_protein_family
Medical condition
branching of neurites, partly by positive regulatory mechanisms of HES1 and CREB1 gene expression. In the adult hippocampus, a reduction in FOXG1 gene dosage
FOXG1_syndrome
specific TF according to literature or domain structure – No motif [113] CREB1 ENSG00000118260 bZIP Known motif – High-throughput in vitro [114] VTKACGTMA
List of human transcription factors
List_of_human_transcription_factors
Protein domain
ATF7; BACH1; BACH2; BATF; BATF2; CEBPA; CEBPB; CEBPD; CEBPE; CEBPG; CEBPZ; CREB1; CREB3; CREB3L1; CREB3L2; CREB3L3; CREB3L4; CREB5; CREBL1; CREM; E4BP4;
BZIP_domain
Southu Korean neuroscietnist (born 1961)
molecules that interplay with other regulatory molecules, such as ApCAM, CREB1, CREB2, C/EBP, and ApAF. Furthermore, Kaang reported that, by genetically
Kaang_Bong-kiun
Protein-coding gene in the species Homo sapiens
interactions. COX8A appears to interact with NPM1, MAGEA4, EDDM3B, BATF, AMBP, CREB1, and NCOR1. GRCh38: Ensembl release 89: ENSG00000176340 – Ensembl, May 2017
COX8A
Protein-coding gene in the species Homo sapiens
transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit
PRKAR2B
Protein-coding gene in humans
expressed in several different cancers. CEBPB has been shown to interact with: CREB1, CRSP3 DNA damage-inducible transcript 3, EP300, Estrogen receptor alpha
CEBPB
Protein-coding gene in the species Homo sapiens
neurodegeneration. HTATIP has been shown to interact with: Androgen receptor, BCL3, CREB1, ETV6, EDNRA FANCD2, HDAC7A, Mdm2, Myc, and PLA2G4A. PXR GRCh38: Ensembl
KAT5
DNA-binding protein involved in methylation
transcriptional activator, through recruiting the transcription factor CREB1. This was an unexpected finding which suggests that MeCP2 is a key transcriptional
MECP2
Enzyme found in humans
kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-Fos. Alternate transcriptional splice variants of this gene have been
RPS6KA4
(cAMP)-protein kinase element-binding protein CREB1 path way. Since histone acetylation and the cAMP-PKA-CREB1 pathway are extremely important for normal
Deficiency of RbAp48 protein and memory loss
Deficiency_of_RbAp48_protein_and_memory_loss
Damage to nervous tissue
the regenerative capacity of peripheral neurons including ASCL1, ATF3, CREB1, HIF1α, JUN, KLF6, KLF7, MYC, SMAD1, SMAD2, SMAD3, SOX11, SRF, STAT3, TP53
Nerve_injury
Protein-coding gene in the species Homo sapiens
including 97 co-complex interactions. NDUFV1 appears to interact with EWSR1, CREB1, NCOR1, and VDAC1. GRCh38: Ensembl release 89: ENSG00000167792 – Ensembl
NDUFV1
Type of tumor which affects children and adolescents
characterization of the recurrent chromosomal rearrangements that result in the EWSR1-CREB1, t(12;22)(q13;q12) EWSR1-ATF1, and t(12;16)(q13;p11) FUS-ATF1 gene fusions
Angiomatoid fibrous histiocytoma
Angiomatoid_fibrous_histiocytoma
Protein-coding gene in the species Homo sapiens
that POLB expression is tightly regulated. POLB gene is upregulated by CREB1 transcription factor's binding to the cAMP response element (CRE) present
DNA_polymerase_beta
Mammalian protein found in Homo sapiens
between androgen receptor and extracellular signal-regulated kinase (ERK) via CREB1 which can be inhibited by anti-androgens. PIP expression is necessary for
Prolactin-induced_protein
Protein-coding gene in the species Homo sapiens
crest by enhancing BMP signaling. FHL3 has been shown to interact with: CREB1, CTBP2, FHL2, ITGA7 and KLF3. GRCh38: Ensembl release 89: ENSG00000183386
FHL3
Protein-coding gene in the species Homo sapiens
tcataaaAACAttccag - VTATA.02 Mammalian C-type LTR TATA box 0.895 tgtcaTAAAaacattcc - CREB1.02 cAMP-responsive element binding protein 1 0.949 tggaaGTGAtgtcataaaaac
C1orf185
Mammalian protein found in Homo sapiens
Cellular component cytoplasm ATF1-ATF4 transcription factor complex ATF4-CREB1 transcription factor complex transcription regulator complex dendrite membrane
ATF4
Enzyme
expression of immediate early genes. RPS6KA5 has been shown to interact with CREB1. GRCh38: Ensembl release 89: ENSG00000100784 – Ensembl, May 2017 GRCm38:
RPS6KA5
Protein-coding gene in the species Homo sapiens
Interactor Function CREB1 (cAMP responsive element binding protein 1) Induction of growth, differentiation, migration, adhesion, and cell survival in
C16orf71
short-segment; 142623; PMX2B Histiocytoma, angiomatoid fibrous, somatic; 612160; CREB1 HMG-CoA synthase-2 deficiency; 605911; HMGCS2 Hodgkin's lymphoma; 236000;
List_of_OMIM_disorder_codes
Q96SW2 3540 CRCP HGNC:17888; O75575 3541 CRCT1 HGNC:29875; Q9UGL9 3542 CREB1 HGNC:2345; P16220 3543 CREB3 HGNC:2347; O43889 3544 CREB3L1 HGNC:18856;
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
Protein-coding gene in the species Homo sapiens
through the PKA-CREB1-CPB pathway. Hence one possible therapeutic approach to restore age-related memory loss is the use of PKA-CREB1-CPB pathway stimulating
RBBP4
Protein-coding gene in the species Homo sapiens
to interact with: Androgen receptor, BRCA1, CTNNB1, CD18, CD29, CD49c, CREB1, EIF6, FHL3, IGFBP5, ITGA7, ITGB6, MAPK1, PSEN2, TRAF6, TTN, ZNF638, and
FHL2
Protein-coding gene in the species Homo sapiens
polyadenylation sites found in this gene. FHL5 has been shown to interact with CREB1 and CAMP responsive element modulator. GRCh38: Ensembl release 89: ENSG00000112214
FHL5
Precursor microRNA family
Pallante P, Rubio I, Santoro M, Croce CM, Fusco A (October 2011). "A TSH-CREB1-microRNA loop is required for thyroid cell growth". Molecular Endocrinology
Mir-28 microRNA precursor family
Mir-28_microRNA_precursor_family
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Girl/Female
English American Greek Latin
Name invented in the 16th century for a heroine of the book 'Arcadia', by Sir Philip Sidney.
Boy/Male
Muslim
Girl/Female
Hindu
Girl/Female
Muslim/Islamic
She was a companion
Boy/Male
Anglo Saxon
From Birdoswald.
Boy/Male
Australian, Greek
Vigilant Guardian; Shining
Surname or Lastname
English
English : from Old English cufle ‘cloak’, hence a nickname for an habitual wearer of a cloak or perhaps a metonymic occupational name for a cloak maker.
Boy/Male
American, Australian, Bengali, German, Hebrew, Indian
Comforter
Boy/Male
Biblical
Rescued from danger.
Surname or Lastname
English
English : originally, like most of the English names derived from the ranks of nobility, either a nickname or an occupational name for a servant employed in a noble household. The vocabulary word is a native one, from Old English eorl ‘nobleman’, and in the Middle Ages was often used as an equivalent of Norman Count.
CREB1
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