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BTLA

  • BTLA
  • Protein-coding gene in the species Homo sapiens

    B- and T-lymphocyte attenuator or BTLA (also known as cluster of differentiation 272 or CD272) is a protein that belongs to the CD28 immunoglobulin superfamily

    BTLA

    BTLA

    BTLA

  • Bluetooth Special Interest Group
  • Standards organization for Bluetooth technologies

    Patent/Copyright License Agreement and Bluetooth Trademark License Agreement ("BTLA"). An overview of both processes including steps of the processes, types

    Bluetooth Special Interest Group

    Bluetooth Special Interest Group

    Bluetooth_Special_Interest_Group

  • Immunoreceptor tyrosine-based inhibitory motif
  • PMID 14707061. S2CID 8440407. Zeng C, Wu T, Zhen Y, Xia XP, Zhao Y (December 2005). "BTLA, a new inhibitory B7 family receptor with a TNFR family ligand" (PDF). Cellular

    Immunoreceptor tyrosine-based inhibitory motif

    Immunoreceptor_tyrosine-based_inhibitory_motif

  • Peripheral tolerance
  • Removal of autoreactive T and B cells outside of the primary lymphoid organs

    to Treg. iDCs are more potent Treg inducers than lymph node–resident DCs. BTLA is a crucial molecule for DCs-mediated Treg conversion. Tolerogenic DCs express

    Peripheral tolerance

    Peripheral_tolerance

  • CD28 family receptor
  • Group of regulatory cell surface receptors

    ICOS, act as positive regulators of T cell function while another three, BTLA, CTLA-4 and PD-1 act as inhibitors. Ligands for the CD28 receptor family

    CD28 family receptor

    CD28 family receptor

    CD28_family_receptor

  • Immune checkpoint
  • Regulators of the immune system

    cells and tumor-associated macrophages and plays a role in tumour escape. BTLA: This molecule, short for B and T Lymphocyte Attenuator and also called CD272

    Immune checkpoint

    Immune checkpoint

    Immune_checkpoint

  • Immunoglobulin domain
  • Protein domain

    include: A1BG ACAM ADAMTSL1 ADAMTSL3 AGER ALCAM AMIGO1 AMIGO2 AXL BCAM BOC BSG BTLA C10orf72 C20orf102 CADM1 CADM3 CD200 CD22 CD276 CD33 CD4 CDON CEACAM1 CEACAM16

    Immunoglobulin domain

    Immunoglobulin domain

    Immunoglobulin_domain

  • Barrel threads
  • Method to attach a weapon barrel and receiver

    Release BAT M model tenon thread profile - Bat Machine Co. Inc. BAT HR & BTLA models tenon thread profile - Bat Machine Co. Inc. BAT CT model tenon thread

    Barrel threads

    Barrel_threads

  • Sanford Burnham Prebys
  • Non-profit medical research institute

    Supporting Therapeutic Potential of Activating the Immune Checkpoint Receptor BTLA in SLE". ACR Meeting Abstracts. Retrieved 2025-05-02. Maruyama, Sonomi; Visser

    Sanford Burnham Prebys

    Sanford Burnham Prebys

    Sanford_Burnham_Prebys

  • PD-L1
  • Mammalian protein found in humans

    CB, Huang C, Wang J, Hong Y, Fan DD, Chen Y, et al. (2023-09-01). "PD-L1/BTLA Checkpoint Axis Exploited for Bacterial Immune Escape by Restraining CD8+

    PD-L1

    PD-L1

    PD-L1

  • Co-stimulation
  • Signal to activate immune cells

    co-stimulatory signals. Apart from CD28; ICOS, 41-BB, OX40, TIM3, CD30, BTLA or CD27 were also shown to play role in the proper formation and later signaling

    Co-stimulation

    Co-stimulation

  • BCL6
  • Transcription factor for converting Naive T cells to TFH

    of anti-lymphoma activity. BCL6 has been shown to interact with * BCOR, BTLA, Ccr7, CD200, C-jun, CREBBP, CXCR5, EP300, EZH2, Gpr183, HDAC1, HDAC4, HDAC7A

    BCL6

    BCL6

    BCL6

  • CD28
  • Mammalian protein found in humans

    subfamily also include homologous receptors ICOS, CTLA4, PD1, PD1H, and BTLA. Nevertheless, only CD28 is expressed constitutively on mouse T cells, whereas

    CD28

    CD28

    CD28

  • Programmed cell death protein 1
  • Mammalian protein found in humans

    Huang C, Wang J, Hong Y, Fan DD, Chen Y, et al. (September 2023). "PD-L1/BTLA Checkpoint Axis Exploited for Bacterial Immune Escape by Restraining CD8+

    Programmed cell death protein 1

    Programmed cell death protein 1

    Programmed_cell_death_protein_1

  • Immunoglobulin superfamily
  • Large protein superfamily of cell surface and soluble proteins

    CD28, CTLA-4, program death-1 (PD-1), the B- and T-lymphocyte attenuator (BTLA, CD272), and the inducible T-cell co-stimulator (ICOS, CD278); and their

    Immunoglobulin superfamily

    Immunoglobulin superfamily

    Immunoglobulin_superfamily

  • List of human clusters of differentiation
  • drugs (2016). CD272 BTLA (B- and T-lymphocyte attenuator); expression induced during activation of T cells. Like PD1 and CTLA4, BTLA interacts with a B7

    List of human clusters of differentiation

    List_of_human_clusters_of_differentiation

  • VTCN1
  • Protein-coding gene in the species Homo sapiens

    Sim J, Zang X, Murphy TL, Russell JH, Allison JP, Murphy KM (July 2003). "BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1"

    VTCN1

    VTCN1

    VTCN1

  • Non-catalytic tyrosine-phosphorylated receptor
  • Group of cell surface receptors expressed by leukocytes

    SIGLEC2 CD28 family B7 family of membrane proteins CD28, CTLA-4, ICOS, BTLA CD200R family CD200 CD200R1, CD5, CD6 Signal-regulatory protein (SIRP) family

    Non-catalytic tyrosine-phosphorylated receptor

    Non-catalytic_tyrosine-phosphorylated_receptor

  • List of human protein-coding genes 1
  • HGNC:1132; Q14201 1714 BTG4 HGNC:13862; Q9NY30 1715 BTK HGNC:1133; Q06187 1716 BTLA HGNC:21087; Q7Z6A9 1717 BTN1A1 HGNC:1135; Q13410 1718 BTN2A1 HGNC:1136; Q7KYR7

    List of human protein-coding genes 1

    List_of_human_protein-coding_genes_1

  • Herpesvirus entry mediator
  • Protein-coding gene in the species Homo sapiens

    CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM 2aw2: Crystal structure of the human BTLA-HVEM complex

    Herpesvirus entry mediator

    Herpesvirus entry mediator

    Herpesvirus_entry_mediator

  • PDCD1LG2
  • Protein-coding gene in the species Homo sapiens

    Huang C, Wang J, Hong Y, Fan DD, Chen Y, et al. (September 2023). "PD-L1/BTLA Checkpoint Axis Exploited for Bacterial Immune Escape by Restraining CD8+

    PDCD1LG2

    PDCD1LG2

    PDCD1LG2

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Online names & meanings

  • Sirena
  • Girl/Female

    Greek

    Sirena

    Named for the Sirens.

  • YAMIN
  • Male

    Hebrew

    YAMIN

    Variant spelling of Hebrew Yamiyn, YAMIN means "the right hand," "the right side," or "the right quarter."

  • Abduz Zahir |
  • Boy/Male

    Muslim

    Abduz Zahir |

    Slave of the manifest

  • Periyakaruppan
  • Boy/Male

    Hindu, Indian, Traditional

    Periyakaruppan

    Lord Periyakaruppan

  • Bahhas
  • Boy/Male

    Arabic

    Bahhas

    Scholar

  • Reja
  • Girl/Female

    Arabic, German, Muslim

    Reja

    Good News

  • Lira
  • Girl/Female

    Hindu

    Lira

    Devotee of Goddess Kali

  • TALI
  • Female

    Egyptian

    TALI

    , a priestess of Amen Ra.

  • Trinity
  • Girl/Female

    Hindu

    Trinity

    Three, Triple

  • Mahra
  • Girl/Female

    Arabic

    Mahra

    Horse

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BTLA

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