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TA SE-SERT

  • Clomipramine
  • achieve up to 100.0% SERT occupancy with clomipramine and up to 93.6% SERT occupancy with fluvoxamine. Other studies have found 83% SERT occupancy with 20 mg/day

    Clomipramine

  • Mazindol
  • following trends are apparent: Removal of the tertiary alcohol improves DAT and SERT binding without substantially reducing NET affinity. This compound has been

    Mazindol

  • Reverse transport
  • located along the plasma membrane of neurons (specifically, DAT, NET, and SERT). The precise mechanisms by which amphetamines and other monoamine releasing

    Reverse transport

  • Ciclazindol
  • extent as a dopamine reuptake inhibitor. Ciclazindol has no effects on the SERT, 5-HT receptors, mACh receptors, or α-adrenergic receptors, and has only

    Ciclazindol

  • Escitalopram
  • escitalopram has the highest selectivity for the serotonin transporter (SERT) compared to the norepinephrine transporter (NET), making the side-effect

    Escitalopram

  • Selective serotonin reuptake inhibitor
  • should be performed on people with DMR to evaluate serotonin transporter (SERT) activity. They also urge practitioners to exercise caution when prescribing

    Selective serotonin reuptake inhibitor

  • MDMA
  • levels, SERT is crucial for the process of 5-HT neurotransmission (Green et al., 2003). MDMA downregulates SERT function without altering SERT mRNA or

    MDMA

  • Monoamine releasing agent
  • the monoamine transporters (MATs), including the serotonin transporter (SERT), norepinephrine transporter (NET), and/or dopamine transporter (DAT), causing

    Monoamine releasing agent

  • Tramadol
  • occupation of the serotonin transporter (SERT) in the thalamus. The estimated median effective dose (ED50) for SERT occupancy hence was 98.1 mg, which was

    Tramadol

  • 5-MAPB
  • NETTooltip Norepinephrine transporter DATTooltip Dopamine transporter DAT/SERT ratio (S)-5-MAPB 67 ND 258 0.26 75% (S)-5-MAPB 80 ND 632 0.13 (RS)-5-MAPB

    5-MAPB

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