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What is the meaning of hdm2. Phrases containing hdm2
See meanings and uses of hdm2!
What is the meaning of hdm2. Phrases containing hdm2
See meanings and uses of hdm2!hdm2
hdm2
ubiquitin ligase HDM2, a protein that mediates p53 ligation and tagged destruction, through ubiquitination. The mechanism for this neuroblastoma HDM2 hyperactivity
human homologue of this protein was later identified and is sometimes called Hdm2. Further supporting the role of mdm2 as an oncogene, several human tumor
designed to mimic P53 and bind HDM2. The molecule enters cells through passive diffusion, and this mimic was shown to stabilize HDM2 in cell culture. Binuclear
through a continuous degradation of p53. A protein called Mdm2 (also called HDM2 in humans), binds to p53, preventing its action and transports it from the
classified into 7 subfamilies termed histone lysine demethylases, i.e., HDM2 to HDM7, with each subfamily having multiple members. These HDMs are characterized
Masterson, Philip; O'Connor, Mark J.; Jackson, Stephen P. (2005). "hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage"
Mondal S, Rutka JT (June 2008). "p14ARF interacts with DAXX: effects on HDM2 and p53". Cell Cycle. 7 (12): 1836–1850. doi:10.4161/cc.7.12.6025. PMID 18583933
(February 2005). "Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells". Journal of Medicinal Chemistry.
p53 tumor suppressor protein, microarray studies which targeted Hdmx and Hdm2, both p53 negative regulators, revealed YPEL3 as a potential p53 regulated
2008.0575. PMID 19106041. Frum R, Busby SA, Ramamoorthy M, et al. (2007). "HDM2-binding partners: interaction with translation elongation factor EF1alpha"
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hdm2
Astrological/horoscope meaning of hdm2. hdm2 means: undefined
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H: Meaning of H in the acronym hdm2 means: H looks like a ladder. As a ladder, it implies rising from the bottom with effort. H shows inspiration and firmness. The connected of the uprights parts indicate impartiality. The letter H is upright and stable indicating calmness and self-reliance.
D: Meaning of D in the acronym hdm2 means: D is a closed letter indicating self sufficiency. It displays self-reliance, a caring attitude and broadmindedness. It's broadmindedness can be seen in the fat that the letter D has a side that looks like an upright pole, it branches from the top and bottom to explore outwards, gain worldly knowledge, but its steady and slow, meticulous and self-reliance brings it back to itself.
M: Meaning of M in the acronym hdm2 means: While M stands on two points, it has three projections pointing downwards. M is dracious, stable and temperamental. M could also be overwhelming with a great strenght of character and a strong in mind.
2: Meaning of 2 in the acronym hdm2 means: undefined
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