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  • Cyclooxygenase-2 inhibitor
  • ubiquitin ligase HDM2, a protein that mediates p53 ligation and tagged destruction, through ubiquitination. The mechanism for this neuroblastoma HDM2 hyperactivity

  • Mdm2
  • human homologue of this protein was later identified and is sometimes called Hdm2. Further supporting the role of mdm2 as an oncogene, several human tumor

  • Spiroligomer
  • designed to mimic P53 and bind HDM2. The molecule enters cells through passive diffusion, and this mimic was shown to stabilize HDM2 in cell culture. Binuclear

  • P53
  • through a continuous degradation of p53. A protein called Mdm2 (also called HDM2 in humans), binds to p53, preventing its action and transports it from the

  • Α-Ketoglutaric acid
  • classified into 7 subfamilies termed histone lysine demethylases, i.e., HDM2 to HDM7, with each subfamily having multiple members. These HDMs are characterized

  • P16
  • Mondal S, Rutka JT (June 2008). "p14ARF interacts with DAXX: effects on HDM2 and p53". Cell Cycle. 7 (12): 1836–1850. doi:10.4161/cc.7.12.6025. PMID 18583933

  • Heterogeneous ribonucleoprotein particle
  • Masterson, Philip; O'Connor, Mark J.; Jackson, Stephen P. (2005). "hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage"

  • Thermal shift assay
  • (February 2005). "Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells". Journal of Medicinal Chemistry.

  • YPEL3
  • p53 tumor suppressor protein, microarray studies which targeted Hdmx and Hdm2, both p53 negative regulators, revealed YPEL3 as a potential p53 regulated

  • Azurin
  • (March 2013). "A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced

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Astrological/horoscope meaning of hdm2. hdm2 means: undefined

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    H: Meaning of H in the acronym hdm2 means: H looks like a ladder. As a ladder, it implies rising from the bottom with effort. H shows inspiration and firmness. The connected of the uprights parts indicate impartiality. The letter H is upright and stable indicating calmness and self-reliance.

    D: Meaning of D in the acronym hdm2 means: D is a closed letter indicating self sufficiency. It displays self-reliance, a caring attitude and broadmindedness. It's broadmindedness can be seen in the fat that the letter D has a side that looks like an upright pole, it branches from the top and bottom to explore outwards, gain worldly knowledge, but its steady and slow, meticulous and self-reliance brings it back to itself.

    M: Meaning of M in the acronym hdm2 means: While M stands on two points, it has three projections pointing downwards. M is dracious, stable and temperamental. M could also be overwhelming with a great strenght of character and a strong in mind.

    2: Meaning of 2 in the acronym hdm2 means: undefined

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