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Protein-coding gene in the species Homo sapiens
Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 was initially purified from the epidermis
KLK7
Subgroup of serine proteases
particular, KLK7 likely acts at the end of an enzyme cascade involving other members. For example, KLK5 may auto-activating, then activate KLK7, or KLK6
Kallikrein
Protein-coding gene in the species Homo sapiens
been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular
Kallikrein-5
Skin peeling
corneodesmosome-degrading kallikrein family members, especially KLK1, KLK5, and KLK7. Kallikreins are serine proteases; packaged within the lamellar bodies and
Desquamation
Protein-coding gene in humans
in the epidermis. It is able to the inhibit the chymotryptic activity of KLK7. This gene encodes a member of the alpha-macroglobulin superfamily. The encoded
A2ML1
Secretory organelles
distinct aggregates of the secreted components glucosylceramide, cathepsin D, KLK7, KLK8 and corneodesmosin. Transportation of molecules via lamellar bodies
Lamellar_bodies
Protein-coding gene in the species Homo sapiens
regulation of desquamation via its ability to selectively inhibit KLK5, KLK7 and KLK14. Recombinant full length LEKTI inhibits the exogenous serine proteases
LEKTI
Topics referred to by the same term
corneum chymotryptic enzyme, an enzyme class KLK7, a serine protease that in humans is encoded by the KLK7 gene This disambiguation page lists articles
Kallikrein_7
Type of enzyme inhibition
isolating fukugetin, it was placed with KLK1, KLK2, KLK3, KLK4, KLK5, KLK6, and KLK7 in varying concentrations. This allowed for the analysis of enzyme kinetics
Mixed_inhibition
Stratum corneum chymotryptic enzyme (EC 3.4.21.117, kallikrein 7, SCCE, KLK7, PRSS6, hK7) is an enzyme. This enzyme catalyses the following chemical reaction
Stratum corneum chymotryptic enzyme
Stratum_corneum_chymotryptic_enzyme
Medical condition
expressed in the skin. Potential endogenous targets of LEKTI include KLK5, KLK7 and KLK14. These enzymes are involved in various aspects of epidermal remodelling
Netherton_syndrome
Mammalian protein found in Homo sapiens
epidermal proteases involved in maintaining skin homeostasis, including KLK5, KLK7 and KLK14. SPINK6 is a member of a gene family cluster located on chromosome
SPINK6
Terminally differentiated keratinocytes
by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7". The Journal of Investigative Dermatology. 122 (5): 1235–44. doi:10
Corneocyte
amino acids, its main function is modulating the insulin inhibiting protease KLK7, mainly in adipose tissue. Among other functions, Serpin A12 performs insulin-sensitizing
SERPINA12
Mammalian protein found in Homo sapiens
desquamation to occur, corneodesmosomes need to be fully degraded. KLK5 and KLK7 are two serine proteases that degrade corneodesmosomes. LEKTI-2 regulates
LEKTI-2
Protein-coding gene in the species Homo sapiens
by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7". J. Invest. Dermatol. 122 (5): 1235–44. doi:10.1111/j.0022-202X.2004
Corneodesmosin
Protein-coding gene in the species Homo sapiens
PDB id codes 1GVL, 1L2E, 1LO6, 3VFE, 4D8N Identifiers Aliases KLK6, Bssp, Klk7, PRSS18, PRSS9, SP59, hK6, kallikrein related peptidase 6 External IDs OMIM:
KLK6
HGNC:6365; Q9Y5K2 8286 KLK5 HGNC:6366; Q9Y337 8287 KLK6 HGNC:6367; Q92876 8288 KLK7 HGNC:6368; P49862 8289 KLK8 HGNC:6369; O60259 8290 KLK9 HGNC:6370; Q9UKQ9
List of human protein-coding genes 4
List_of_human_protein-coding_genes_4
and the sixth variant (K5R_I10H_F12W) showed dual-inhibition of KLK5 and KLK7, improved KLK5 inhibition potency, and specificity for KLK5 and KLK14. The
Sunflower_trypsin_inhibitor
KLK7
KLK7
KLK7
KLK7
Girl/Female
Hindu
The river Yamuna
Boy/Male
Tamil
A message or tidings or that which is heard, Rock that can penetrate metal
Surname or Lastname
English
English : unexplained; perhaps, as Reaney and Wilson propose, a variant of Welsh Beynon. However, the modern surname in the UK is found mainly in Lincolnshire, on the other side of the country from Wales.
Boy/Male
Hindu, Indian
Brave
Girl/Female
English American Russian
Abbreviation of Tatiana which is feminine of the Roman family clan name Tatius.
Girl/Female
Tamil
Bird
Boy/Male
Australian, Italian, Russian, Slavic
Yahweh is Gracious
Girl/Female
Biblical
Heap of salt.
Girl/Female
Hindu, Indian
Coin in Ancient Times
Boy/Male
Indian
Mallik means great
KLK7
KLK7
KLK7
KLK7
KLK7