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IPATASERTIB

  • Ipatasertib
  • Chemical compound

    Ipatasertib (RG7440) is an experimental cancer drug in development by Roche. It is a small molecule inhibitor of AKT, which is a key component of the

    Ipatasertib

    Ipatasertib

    Ipatasertib

  • PI3K/AKT/mTOR pathway
  • Cell cycle regulation pathway

    least two prior therapies. AKT is downstream to PI3K and is inhibited by Ipatasertib. Akt is an AGC-family kinase and a central, integral signaling node of

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR_pathway

  • Protein kinase B
  • Set of three serine threonine-specific protein kinases

    solid tumors. with a study of AZD5363 with olaparib reporting in 2016. Ipatasertib is in phase II trials for breast cancer. Akt isoform activation is associated

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • Ming Tatt Cheah
  • Malaysian biologist

    most recently for Tecentriq® (PD-L1 Ab), tiragolumb (TIGIT Ab), and ipatasertib (AKT inhibitor) in oncology, Ocrevus® (CD20 Ab) in multiple sclerosis

    Ming Tatt Cheah

    Ming_Tatt_Cheah

  • Nirogacestat
  • Chemical compound

    leading to cell proliferation. Moreover, combination with an AKT inhibitor ipatasertib further enhanced apoptotic promotion in malignant R-CHOP-resistant lymphocytes

    Nirogacestat

    Nirogacestat

    Nirogacestat

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IPATASERTIB

Online names & meanings

  • Anantya | அநஂதா, அநஂதயா
  • Girl/Female

    Tamil

    Anantya | அநஂதா, அநஂதயா

    Endless, Eternal

  • Yoshan
  • Boy/Male

    Australian, Indian

    Yoshan

    Thought

  • Zatinga
  • Girl/Female

    Assamese, Indian

    Zatinga

    River

  • Vivash
  • Boy/Male

    Hindu

    Vivash

    Dawning, Exile, Bright

  • Mani Shankar
  • Boy/Male

    Hindu

    Mani Shankar

    Lord Shiva

  • Jopp
  • Surname or Lastname

    English

    Jopp

    English : variant of Job.South German : from the personal name, either a derivative of Hiob, the German form of Job, or a reduced form of Jakob.

  • Kuwanyauma
  • Girl/Female

    Native American

    Kuwanyauma

    Butterfly showing beautiful wings.

  • Corbett
  • Boy/Male

    French American English

    Corbett

    Raven.

  • Houlton
  • Surname or Lastname

    English

    Houlton

    English : variant of Holton.

  • VANNI
  • Male

    Italian

    VANNI

    Short form of Italian Giovanni, VANNI means "God is gracious."

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IPATASERTIB

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