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  • Tet methylcytosine dioxygenase 2
  • Tet methylcytosine dioxygenase 2 (TET2) is a human gene. It resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss

  • Myeloproliferative neoplasm
  • often associated with a somatic mutation, for example in the JAK2, CALR, TET2, and MPL gene markers. In rare cases, some MPNs such as primary myelofibrosis

  • TET enzymes
  • The three related TET genes, TET1, TET2 and TET3 code respectively for three related mammalian proteins TET1, TET2, and TET3. All three proteins possess

  • Base excision repair
  • oxidized by the ten-eleven translocation (TET) family of dioxygenases (TET1, TET2, TET3) to generate 5-hydroxymethylcytosine (5hmC). In successive steps TET

  • Itaconic acid
  • from binding to and thereby activating the isolated TET2 protein in a cell-free system; b) TET2 gene knockout bone marrow-derived macrophages (i.e.,

  • Clonal hematopoiesis
  • X-inactivation skew also had mutations in the hematologic-malignancy-associated gene TET2. In 2014, several independent studies confirmed the presence of malignancy-associated

  • Chymotrypsin
  • However, evidence for similar general-acid catalysis of the k2 reaction (Tet2) has been controverted; apparently water provides a proton to the amine leaving

  • Wilms tumor protein
  • WT1 is mutated in a mutually exclusive manner with TET2, IDH1, and IDH2 in acute myeloid leukemia. TET2 can be recruited by WT1 to its target genes and activates

  • Genome
  • (5hmC) driven by high levels of the ten-eleven dioxygenase enzymes TET1 and TET2. Genomes are more than the sum of an organism's genes and have traits that

  • Primary myelofibrosis
  • functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1". Leukemia. 24 (6): 1128–1138. doi:10.1038/leu

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Astrological/horoscope meaning of tet2. tet2 means: undefined

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    T: Meaning of T in the acronym tet2 means: T is a vertical strand crossed at the top by a horizontal strand. With the top strand balanced in the middle by the vertical strand, T shows balance and stability in its ways. It is also forgoing and spiritual. With the top strand projected up by the bottom strand, T is highly ambitious, but also kind to others as it can let others rest on its horizontal top. This makes T selfless, cooperative, womanly and dutiful. It also displays a high degree of generosity and liberalism.

    E: Meaning of E in the acronym tet2 means: The letter E has three branches of equal lenghts. These all extend from it's left side. The equal lenghts show a degree of fairness to the outside world. They extend outwards indicating a willingness to learn, think broadly and be more vigorous in understanding. B also implies endowed with good writing abilities, eloquence, resourcefulness. It displays a unique artistic nature and strong enthusaism to get out and know more.

    2: Meaning of 2 in the acronym tet2 means: undefined

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