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  • Machado–Joseph disease
  • disease, Machado's disease, Joseph's disease or spinocerebellar ataxia type 3 (SCA3), is a rare autosomal dominantly inherited neurodegenerative disease that

  • Troriluzole
  • investigated as a potential treatment for spinocerebellar ataxia type 3 (SCA3), obsessive-compulsive disorder, and glioblastoma. It is a prodrug formulation

  • Spinocerebellar ataxia
  • The threshold for symptoms in most forms of SCA is around 35, though for SCA3 it extends beyond 50. Most polyglutamine diseases are dominant due to the

  • Frameshift mutation
  • of the original SCA3 gene product encoding CAG/polyglutamines to GCA/polyalanines. Ribosomal slippage during translation of the SCA3 protein has been

  • Trehalose
  • trehalose (SLS-005) as a potential treatment for spinocerebellar ataxia type 3 (SCA3). In 1832, H.A.L. Wiggers discovered trehalose in an ergot of rye, and in

  • List of awards and nominations received by James Reid
  • the year!". Star Cinema. September 16, 2015. Retrieved August 8, 2016. "#SCA3: Here are the official nominees for the #VoiceonFleek category!". Star Cinema

  • Repeated sequence (DNA)
  • that underlie several types of spinocerebellar ataxias (SCAs-SCA1; SCA2; SCA3; SCA6; SCA7; SCA12; SCA17). Similar to Huntington's disease, the polyglutamine

  • Slipped strand mispairing
  • in the SCA1gene), Machado-Joseph disease ( trinucleotide expansion in the SCA3 gene), myotonic dystrophy ( trinucleotide expansion in the DMPK gene), and

  • Autosomal dominant cerebellar ataxia
  • SCA2, SCA3, SCA17, and DRPLA. This first subclass is the most common of Type 1 ADCAs with SCA3 being the most common subtype of all of Type 1. SCA3, Machado-Joseph

  • Trinucleotide repeat disorder
  • - 35 49 - 88 SCA2 (Spinocerebellar ataxia Type 2) ATXN2 14 - 32 33 - 77 SCA3 (Spinocerebellar ataxia Type 3 or Machado-Joseph disease) ATXN3 12 - 40 55

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Astrological/horoscope meaning of sca3. sca3 means: undefined

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    S: Meaning of S in the acronym sca3 means: S is a single strand that goes forward and backwards. It shows a willingness to explore. Friendliness, perceptiveness and accommodating are all S qualities. The ends pointing forward and backwards shows a conflicting nature with itself and a degree of puzzlement.

    C: Meaning of C in the acronym sca3 means: C is a letter opened at one end. It exemplies openness, a welcoming attitude and the desire to share. This means healthy behaviours, confidence towards the outside world, positive thinking, striking, scholarstic abilities shown by an open-mindedness, lively and gregarious and triumphant. C curves aaway from the left to indicate prudence, nervousness in unfamiliar territory, tense and anxious behaviours when faced with the unknown.

    A: Meaning of A in the acronym sca3 means: The letter A has two bars connected at a pointed edge and a cross bar holding them together. From an open end to a pointed edge signifies that all energies are trained to a point to achieve the most singularly important goal. The cross bar shows caution. Failure is avoided by stringing all required resources together. A also looks like a Pyramid with the peak as the apex of the Pyramid. Pyramids are iconic. A therefore symbolizes prominence and a desire to be recognized for ones achievements. The cross bar also represents a rung in ladder. To get to the top, one has to first step on the rung. It also means originality, a strong will power and an enterprising ability. The upper-case version consists of the two slanting sides of a triangle, crossed in the middle by a horizontal bar. It shows aspiration, the dominance to be successful, positive attitude, an optimistic world view and egotism.

    3: Meaning of 3 in the acronym sca3 means: undefined

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