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  • KRP (biochemistry)
  • function is to separate the duplicated centrosomes during mitosis. Kinesin-13 MCAK (Mitotic Centromere-Associated Kinesin) is a KRP that is involved in resolving

  • Spindle apparatus
  • depolymerization activity including the well-studied mammalian MCAK and Xenopus XKCM1. MCAK localizes to the growing tips of microtubules at kinetochores

  • CKAP5
  • depolymerization by MCAK (KIF2C), and ch-Tog plays an essential role in centrosomal microtubule assembly, a function independent of MCAK activity. CKAP5 has

  • Aurora kinase B
  • centromere-associated kinesin (MCAK). Both Aurora B and MCAK localize to the inner centromere during prometaphase. Aurora B has been shown to recruit MCAK to the centromere

  • KIF2C
  • Zhou YD, et al. (October 2002). "Expression of a novel HsMCAK mRNA splice variant, tsMCAK gene, in human testis". Life Sciences. 71 (23): 2741–2757.

  • Microtubule plus-end tracking protein
  • proteins XMAP215 CLASP Motor proteins Tea2 MCAK Dynein HC Other proteins Dam1 Lis1 Kar9 Used in Catastrophe: MCAK Used in Rescue: CLIP-170 CLASP Stabilization:

  • Microtubule associated scaffold protein 2
  • L, Davidson A, Wang F, Yao X (2009). "TIP150 interacts with and targets MCAK at the microtubule plus ends". EMBO Rep. 10 (8): 857–65. doi:10.1038/embor

  • Treadmilling
  • SL; Zanic, M (June 2020). "Collective effects of XMAP215, EB1, CLASP2, and MCAK lead to robust microtubule treadmilling". Proc Natl Acad Sci U S A. 117 (23):

  • Kinetochore
  • important KinI kinesin controlling the dynamics of the (+) end assembly is MCAK. However, it seems that there are other kinesins implicated. There are two

  • Spindle checkpoint
  • incorrect attachments through control of the microtubule-severing KINI kinesin MCAK, the DASH complex, and the Ndc80/Hec1 complex at the microtubule-kinetochore

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Astrological/horoscope meaning of mcak. mcak means: With a Life Path 1, your numbers are (10/1, 19/1). Individuals with a life path number of 1 are very original, you can have talents as an inventor or innovator of some sort. In any job you choose, your independent attitude can show through. You have very strong personal needs and desires, and you believe that you must always follow your own convictions. You are tired of routine tasks rather quickly and things that require a great attention in details.People with lifet path of 1 are very are ambitious and assertive towards job promotion. Even if they can conceal their aspirations for social reasons, they can be self-centered and demanding in many cases in order to achieve their objectives. For the most part they are very good as a company, friendly, good-natured and wonderful conversationalists. People like you and are attracted to other with similar qualities. It's a good thing that you are, because you are very sensitive to rejection and do not respond to it well. This life path of 1 also suggests that you entered the world with a high level of necessary skills needed to head people or organizations. Your nature is individualistic desires that demand for independence, and the need for personal fulfillment. Many of business leaders, politicians and military leaders are men and women with a life path of 1. You also have a great creative inspiration, and have reached the enthusiasm and momentum to accomplish greater things in life. They are very good at it by keeping the ball rolling; the introduction of new projects is your strength. You are at your best when you stumble upon obstacles and challenges, as this encourages you to fight with strength and boldness. This brings out both your physical and inner varieties of strength. With this strength comes utter determination and ability to lead. As a naturally talented leader, you take responsibly for any situation. You have a tendency to do this, even if it is sometimes not appropriate for you to do this.There are several ways in which the negative side of the number 1 becomes detrimental. 1 always has the option of size as a guide, but it may fail if size is the only mirror through which one examines things. Unfortunately, sometimes you need to follow others for a while before allowing yourself to perform, and this can be a difficult bitcoin?. When a person with a Life Path 1 is not fully developed and the negative side of it expresses itself, the person appears to be very dependent rather than independent, especially in the early years. If you express these negative trait of the number 1, you are likely to be very dissatisfied with the circumstances, and long for self-control. this could be considered the weak side or the negative qualities of the life path of 1. As an advice to mitigate the negative qualities of 1 which are mainly self-serving, selfish and self-centered, avoid being too bossy and demanding on yourself and others.

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    M: Meaning of M in the acronym mcak means: While M stands on two points, it has three projections pointing downwards. M is dracious, stable and temperamental. M could also be overwhelming with a great strenght of character and a strong in mind.

    C: Meaning of C in the acronym mcak means: C is a letter opened at one end. It exemplies openness, a welcoming attitude and the desire to share. This means healthy behaviours, confidence towards the outside world, positive thinking, striking, scholarstic abilities shown by an open-mindedness, lively and gregarious and triumphant. C curves aaway from the left to indicate prudence, nervousness in unfamiliar territory, tense and anxious behaviours when faced with the unknown.

    A: Meaning of A in the acronym mcak means: The letter A has two bars connected at a pointed edge and a cross bar holding them together. From an open end to a pointed edge signifies that all energies are trained to a point to achieve the most singularly important goal. The cross bar shows caution. Failure is avoided by stringing all required resources together. A also looks like a Pyramid with the peak as the apex of the Pyramid. Pyramids are iconic. A therefore symbolizes prominence and a desire to be recognized for ones achievements. The cross bar also represents a rung in ladder. To get to the top, one has to first step on the rung. It also means originality, a strong will power and an enterprising ability. The upper-case version consists of the two slanting sides of a triangle, crossed in the middle by a horizontal bar. It shows aspiration, the dominance to be successful, positive attitude, an optimistic world view and egotism.

    K: Meaning of K in the acronym mcak means: K like N is another letter that also stands on two stable pillars with right arms slanting upwards and downwards. It looks like a character standing for a pose. It shows an alluring personality, its openess indicates tolerance, its is ready to lend a hand. K is also passionate and culture oriented.

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