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  • Iron-responsive element-binding protein
  • IRP2 degradation in iron-replete cells. IRP2 is regulated by the F-Box FBXL5 which activate the ubiquitination and then the degradation of IRP2. IRP2

  • Otmar Szafnauer
  • Year Entrant 1 2 3 4 5 6 7 8 9 10 Pos Points 1994 IRP1 22 IRP2 19 500 WGI 26 BFR 18 TOP NHS 19 SHA1 19 SHA2 26 LRP ??? ???

  • Human iron metabolism
  • translational level by iron-responsive element-binding proteins IRP1 and especially IRP2. When iron levels are low, these proteins are able to bind to iron-responsive

  • Five prime untranslated region
  • (IRP1 and IRP2). In low levels of iron, the ORF of the target mRNA is blocked as a result of steric hindrance from the binding of IRP1 and IRP2 to the IRE

  • Transferrin receptor
  • iron-responsive element-binding proteins, IRP1 and IRP2. In the absence of iron, one of these proteins (generally IRP2) binds to the hairpin like structure (IRE)

  • FBXL5
  • It promotes IRP2 ubiquitination and then its degradation in an iron- and oxygen-dependent manner. The cryo-EM structure of the FBXL5-IRP2 complex revealed

  • F-box protein
  • stabilise the F-Box FBXL5 and then the complex mediates the ubiquitination of IRP2. F-box protein levels can be regulated by different mechanisms. The regulation

  • LUBAC
  • complex is currently known to be composed of three proteins: heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1), HOIL-1-interacting protein (HOIP), and Shank-associated

  • Tony Buffomante
  • Year Entrant 1 2 3 4 5 6 7 8 9 10 Pos Points 1994 IRP1 21 IRP2 34 IRP3 WGI 13 BFR TOP NHS SHA1 SHA2 LRP ??? ???

  • Yersiniabactin
  • regulators. All four promoter regions of the yersiniabactin region (psn, irp2, ybtA and ybtP) possess a Fur-binding site and are negatively regulated by

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Astrological/horoscope meaning of irp2. irp2 means: undefined

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    I: Meaning of I in the acronym irp2 means: I is a singular letter that thrives on it's on. It is altruistic, concerned, kind, responsive. It shows little tolerance to the outside, it is forceful, alert, self-reliant, loving, egoistic, mutinous, and learned.

    R: Meaning of R in the acronym irp2 means: Letter R sits comfortably on two legs that are a litlle spread apart. It displays great strength. It's close top to itself is uncaring, impetuous, and insensitive.

    P: Meaning of P in the acronym irp2 means: P has a heavy top standing on just a point to show it's strenght. It means strong, the ability tp perceive weakness and opportunities easily and clear-sightedness. By standing on its own, it shows self-centeredness, a thriving attitude and rigorousness. P also shows disconnection, strong will to go even alone and impartiality.

    2: Meaning of 2 in the acronym irp2 means: undefined

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