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  • GPER
  • estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene. GPER binds to and is

  • Fulvestrant
  • activity, fulvestrant is an agonist of the G protein-coupled estrogen receptor (GPER), albeit with relatively low affinity (10–100 nM, relative to 3–6 nM for

  • Endocrine therapy resistance in breast cancer
  • cytoplasmic GPER is associated with lower grade tumors and nuclear GPER with higher rates of metastasis. The signaling pathways associated with the GPER protein

  • Estriol
  • high concentrations (~1,000–10,000 nM) also acts as an antagonist of the GPER, a membrane estrogen receptor where, conversely, estradiol acts as an agonist

  • Estradiol
  • Estradiol also acts as an agonist of membrane estrogen receptors (mERs), such as GPER (GPR30), a recently discovered non-nuclear receptor for estradiol, via which

  • Estrogen
  • and activate rapid-signaling membrane estrogen receptors (mERs), such as GPER (GPR30). In addition to their role as natural hormones, estrogens are used

  • ERx
  • transcription signature induced by estradiol that is independent of the ERα/ERβ and GPER and was identified using the membrane-impermeable estradiol conjugate E2-BSA

  • MIBE
  • nonsteroidal antiestrogen that acts as a dual antagonist of the ERα and the GPER. It was found to prevent estradiol-induced proliferation of MCF-7 breast

  • Norethisterone
  • Equol Estradiol Ethinylestradiol Fulvestrant (ICI-182780) G-1 Genistein GPER-L1 GPER-L2 Hydroxytyrosol Kepone Nicotinic acid Nicotinamide Nonylphenol Oleuropein

  • Spironolactone
  • Equol Estradiol Ethinylestradiol Fulvestrant (ICI-182780) G-1 Genistein GPER-L1 GPER-L2 Hydroxytyrosol Kepone Nicotinic acid Nicotinamide Nonylphenol Oleuropein

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Astrological/horoscope meaning of gper. gper means: With a Life Path 1, your numbers are (10/1, 19/1). Individuals with a life path number of 1 are very original, you can have talents as an inventor or innovator of some sort. In any job you choose, your independent attitude can show through. You have very strong personal needs and desires, and you believe that you must always follow your own convictions. You are tired of routine tasks rather quickly and things that require a great attention in details.People with lifet path of 1 are very are ambitious and assertive towards job promotion. Even if they can conceal their aspirations for social reasons, they can be self-centered and demanding in many cases in order to achieve their objectives. For the most part they are very good as a company, friendly, good-natured and wonderful conversationalists. People like you and are attracted to other with similar qualities. It's a good thing that you are, because you are very sensitive to rejection and do not respond to it well. This life path of 1 also suggests that you entered the world with a high level of necessary skills needed to head people or organizations. Your nature is individualistic desires that demand for independence, and the need for personal fulfillment. Many of business leaders, politicians and military leaders are men and women with a life path of 1. You also have a great creative inspiration, and have reached the enthusiasm and momentum to accomplish greater things in life. They are very good at it by keeping the ball rolling; the introduction of new projects is your strength. You are at your best when you stumble upon obstacles and challenges, as this encourages you to fight with strength and boldness. This brings out both your physical and inner varieties of strength. With this strength comes utter determination and ability to lead. As a naturally talented leader, you take responsibly for any situation. You have a tendency to do this, even if it is sometimes not appropriate for you to do this.There are several ways in which the negative side of the number 1 becomes detrimental. 1 always has the option of size as a guide, but it may fail if size is the only mirror through which one examines things. Unfortunately, sometimes you need to follow others for a while before allowing yourself to perform, and this can be a difficult bitcoin?. When a person with a Life Path 1 is not fully developed and the negative side of it expresses itself, the person appears to be very dependent rather than independent, especially in the early years. If you express these negative trait of the number 1, you are likely to be very dissatisfied with the circumstances, and long for self-control. this could be considered the weak side or the negative qualities of the life path of 1. As an advice to mitigate the negative qualities of 1 which are mainly self-serving, selfish and self-centered, avoid being too bossy and demanding on yourself and others.

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    G: Meaning of G in the acronym gper means: G is like C, but with the bottom end growing upwards. G wants to grasp as much as it can. It shows thoughtfulness, being logical, witty, alert, stretchy, conscientious, intuitive, impetuous, reasoning and uncontrollable.

    P: Meaning of P in the acronym gper means: P has a heavy top standing on just a point to show it's strenght. It means strong, the ability tp perceive weakness and opportunities easily and clear-sightedness. By standing on its own, it shows self-centeredness, a thriving attitude and rigorousness. P also shows disconnection, strong will to go even alone and impartiality.

    E: Meaning of E in the acronym gper means: The letter E has three branches of equal lenghts. These all extend from it's left side. The equal lenghts show a degree of fairness to the outside world. They extend outwards indicating a willingness to learn, think broadly and be more vigorous in understanding. B also implies endowed with good writing abilities, eloquence, resourcefulness. It displays a unique artistic nature and strong enthusaism to get out and know more.

    R: Meaning of R in the acronym gper means: Letter R sits comfortably on two legs that are a litlle spread apart. It displays great strength. It's close top to itself is uncaring, impetuous, and insensitive.

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