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  • TFEB
  • Transcription factor EB is a protein that in humans is encoded by the TFEB gene. TFEB is a master gene for lysosomal biogenesis. It encodes a transcription

  • Lysosome
  • enzymes and membrane proteins is controlled by transcription factor EB (TFEB), which promotes the transcription of nuclear genes. Mutations in the genes

  • Protein kinase B
  • needed] Akt1 regulates TFEB, a master controller of lysosomal biogenesis, by direct phosphorylation at serine 467. Phosphorylated TFEB is excluded from the

  • Akt/PKB signaling pathway
  • Akt regulates TFEB, a master controller of lysosomal biogenesis, by direct phosphorylation of TFEB at serine 467. Phosphorylated TFEB is excluded from

  • Renal cell carcinoma with t(6;11) translocation
  • Renal cell carcinoma with t(6;11) translocation or TFEB-amplified Renal Cell Carcinomas is rare subtype of renal cell carcinoma. The t(6;11)(p21;q12) translocation

  • Andrea Ballabio
  • mutations responsible for many rare genetic diseases. His discovery of the TFEB gene, which controls the functioning of lysosomes, has had a major impact

  • Trehalose
  • research was published showing that trehalose induces autophagy by activating TFEB, a protein that acts as a master regulator of the autophagy-lysosome pathway

  • Folliculin
  • demonstrating conservation of a GAP function for FLCN in lower organisms. TFE3 and TFEB are members of the microphthalmia-associated transcription factor (MiTF)

  • Birt–Hogg–Dubé syndrome
  • tumorigenesis in BHD have been shown to be driven by the constitutive activation of TFEB. BHD can be suggested by clinical findings but is definitively diagnosed

  • Stem cell
  • Mathieu; Schroeder, Timm; Xie, Stephanie Z.; Dick, John E. (August 2021). "TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate"

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Astrological/horoscope meaning of tfeb. tfeb means: With a Life Path 6, your numbers are (6, 15/6, 24/6, 33/6). The Life Path 6 suggests that you came into life with the tools to be the ultimate nurturer, and a beacon for truth, justice, righteousness, and domesticity. You have mature paternal or maternal instincts to nurture more than others your age. Whether at home or at work, you are the predominant caretaker and breadwinner. Beyond community tasks, life revolves around the home and immediate family, the internal numbers. Principles and conservative beliefs are deeply ingrained and define your character.You are idealistic and must be happy to feel useful. The main contribution you make, is that you like to provide advice and are always available serve and support. They are a prime humanitarian. It is your job to serve others, and you start in the home environment. They are very human and realistic about life, and you believe that the most important thing in your life is the home, family and friends.This is the life path to leadership by example and support related, so it is your duty to take responsibility and be ready to help. If you are like most with Life Path 6, you are the one who likes to wear a lot more than your fair share of all costs, and you are always there when needed. In this way, you take ownership and are often an authority on the situation.In romance, 6 are loyal and affectionate. You are able to attract partners that are slightly weaker and worse than yourself; You recommend and can provide protection. The main component of which must prevail in the relationship is complete harmony. They do not work well in stressful relationships, their challenges are to have others monitor for you. It's the same with friends, you are loyal and trustworthy. But there is a tendency for you to be dominant and controlling.It is likely that you feel compelled to function with strength and compassion. They are a friendly and kind person, generous with personal and material resources. Wisdom, balance and understanding are the cornerstones of your life, and tend to define your approach to life in general. Your extraordinary wisdom and the ability to understand other people's problems is likely to start at an early age. In this way you can easily cover the output gap and assume an important role in early life.The Life Path 6 actually has some negative examples, but there are pitfalls to clean the track. You can have a tendency to be overwhelmed by responsibilities and become a slave to others, especially your own family members or close friends. It's easy for you to fall into a pattern of being a helper to others in critical need; They also have a tendency to be too hard on yourself. Misuse of this life cycle generates tendencies to engage exaggeratedly about expansiveness and self-righteousness. Modesty and humility can not move easily. Imposing their views and interfering or meddling in people's matters may be a concern.The natural characteristics of this number are taking on heavy burdens, and on rare occasions, abdicated responsibility by persons with this Life Path 6. With this rejection of responsibility, you will feel very guilty and uncomfortable, and it is harmful on your relationships with others.

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    T: Meaning of T in the acronym tfeb means: T is a vertical strand crossed at the top by a horizontal strand. With the top strand balanced in the middle by the vertical strand, T shows balance and stability in its ways. It is also forgoing and spiritual. With the top strand projected up by the bottom strand, T is highly ambitious, but also kind to others as it can let others rest on its horizontal top. This makes T selfless, cooperative, womanly and dutiful. It also displays a high degree of generosity and liberalism.

    F: Meaning of F in the acronym tfeb means: The letter F is like the letter E, but without the bottom rung. Even without this rung, F shows remarkable stability on its single leg. It means devotion, loving, uncomplaining, defensive, calm. F stands up straights and exemplifies straightforwardness, accountability and harmoniousness.

    E: Meaning of E in the acronym tfeb means: The letter E has three branches of equal lenghts. These all extend from it's left side. The equal lenghts show a degree of fairness to the outside world. They extend outwards indicating a willingness to learn, think broadly and be more vigorous in understanding. B also implies endowed with good writing abilities, eloquence, resourcefulness. It displays a unique artistic nature and strong enthusaism to get out and know more.

    B: Meaning of B in the acronym tfeb means: B is like a with two branches from the top and the bottom that begin to grow out and for some environmental reasons the branches grow back towards each other and then inwards. Contrary to the bold that it might have represented, it displays introvertion, a creative ability to change direction when faced with adversity, shyness of society. It also shows a supportive nature towards others as the branches move inwards to support each other. B is sensitive to feelings and that is observed by the touching of the branches. A temperamental and meditative attitudes are all qualities the letter B holds.

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