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  • MDM4
  • Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene. The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein

  • Triple-negative breast cancer
  • identified as high risk for triple-negative. Changes or mutations in 19p13.1 and MDM4 loci have also been associated with triple-negative breast cancer, but not

  • CDKN2A
  • binding RNA binding DNA binding p53 binding transcription factor binding MDM2/MDM4 family protein binding ubiquitin-protein transferase inhibitor activity SUMO

  • Guillermina Lozano
  • drive tumor development and progression. She also found out how the Mdm2 and Mdm4 proteins work in the body, especially in stopping cancer and controlling

  • List of human protein-coding genes 2
  • HGNC:6972 P21741 9390 MDM1 HGNC:29917 Q8TC05 9391 MDM2 HGNC:6973 Q00987 9392 MDM4 HGNC:6974 O15151 9393 MDN1 HGNC:18302 Q9NU22 9394 MDP1 HGNC:28781 Q86V88

  • P16
  • binding RNA binding DNA binding p53 binding transcription factor binding MDM2/MDM4 family protein binding ubiquitin-protein transferase inhibitor activity SUMO

  • P53
  • HIPK2, HMGB1, HSPA9, Huntingtin, ING1, ING4, ING5, IκBα, KPNB1, LMO3, Mdm2, MDM4, MED1, MAPK9, MNAT1, NDN, NCL, NUMB, NF-κB, P16, PARC, PARP1, PIAS1, CDC14B

  • Mdm2
  • osteosarcomas as well as breast tumors. An additional Mdm2 family member, Mdm4 (also called MdmX), has been discovered and is also an important negative

  • Peroxisome proliferator-activated receptor alpha
  • transcription coactivator binding phosphatase binding NFAT protein binding MDM2/MDM4 family protein binding transcription cis-regulatory region binding RNA polymerase

  • Two-hybrid screening
  • inhibitors in live cells: targeting the interaction of p53 with Mdm2 and Mdm4". Journal of Biomolecular Screening. 19 (4): 516–25. doi:10.1177/1087057113518067

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    M: Meaning of M in the acronym mdm4 means: While M stands on two points, it has three projections pointing downwards. M is dracious, stable and temperamental. M could also be overwhelming with a great strenght of character and a strong in mind.

    D: Meaning of D in the acronym mdm4 means: D is a closed letter indicating self sufficiency. It displays self-reliance, a caring attitude and broadmindedness. It's broadmindedness can be seen in the fat that the letter D has a side that looks like an upright pole, it branches from the top and bottom to explore outwards, gain worldly knowledge, but its steady and slow, meticulous and self-reliance brings it back to itself.

    4: Meaning of 4 in the acronym mdm4 means: undefined

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