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  • AIM2
  • Interferon-inducible protein AIM2 also known as absent in melanoma 2 or simply AIM2 is a protein that in humans is encoded by the AIM2 gene. AIM2 is a cytoplasmic

  • Inflammasome
  • (nucleotide-binding oligomerization domain and leucine-rich repeat-containing receptors), AIM2 (absent in melanoma 2), IFI16 (IFN-inducible protein 16), and pyrin. Through

  • Pyrin domain
  • in melanoma 2-like (AIM2-like) receptors function as recognition of foreign double stranded DNA. Two ALRs with pyrin domains, AIM2 and IFI16, assemble

  • Pyroptosis
  • PAMPs and DAMPs stimuli. Some non-NLR proteins like absent in melanoma 2 (AIM2) and pyrin can also be activated and form inflammasomes. Also, non-inflammasome-forming

  • Thirumala-Devi Kanneganti
  • negatively regulating the NLRP3 inflammasome and inflammatory cell death The AIM2-PANoptosome responds to Francisella and herpes simplex virus 1 infections

  • Endogenous retrovirus
  • binding site for AIM2, meaning that it is necessary for the transcription of AIM2. Researchers had shown this by deleting MER41.AIM2 in HeLa cells using

  • Caspase
  • mediators of Caspase-1 activation are: NOD-like Leucine Rich Repeats (NLRs), AIM2-Like Receptors (ALRs), Pyrin and IFI16. These proteins allow caspase-1 activation

  • Periodic fever, aphthous stomatitis, pharyngitis and adenitis
  • (interleukin-1β, interleukin 1 RN, CASP1, interleukin 18 RAP) and interferon induced (AIM2, IP-10/CXCL10) genes. T cell associated genes (CD3, CD8B) are down regulated

  • List of human protein-coding genes 1
  • HGNC:21411 Q9BRQ8 474 AIFM3 HGNC:26398 Q96NN9 475 AIG1 HGNC:21607 Q9NVV5 476 AIM2 HGNC:357 O14862 477 AIMP1 HGNC:10648 Q12904 478 AIMP2 HGNC:20609 Q13155 479

  • Adam Geballe
  • Esparo NM, Child SJ, Geballe AP PLOS Pathogens. 2016 Oct; 12 10: e1005966 The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular

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Astrological/horoscope meaning of aim2. aim2 means: undefined

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    A: Meaning of A in the acronym aim2 means: The letter A has two bars connected at a pointed edge and a cross bar holding them together. From an open end to a pointed edge signifies that all energies are trained to a point to achieve the most singularly important goal. The cross bar shows caution. Failure is avoided by stringing all required resources together. A also looks like a Pyramid with the peak as the apex of the Pyramid. Pyramids are iconic. A therefore symbolizes prominence and a desire to be recognized for ones achievements. The cross bar also represents a rung in ladder. To get to the top, one has to first step on the rung. It also means originality, a strong will power and an enterprising ability. The upper-case version consists of the two slanting sides of a triangle, crossed in the middle by a horizontal bar. It shows aspiration, the dominance to be successful, positive attitude, an optimistic world view and egotism.

    I: Meaning of I in the acronym aim2 means: I is a singular letter that thrives on it's on. It is altruistic, concerned, kind, responsive. It shows little tolerance to the outside, it is forceful, alert, self-reliant, loving, egoistic, mutinous, and learned.

    M: Meaning of M in the acronym aim2 means: While M stands on two points, it has three projections pointing downwards. M is dracious, stable and temperamental. M could also be overwhelming with a great strenght of character and a strong in mind.

    2: Meaning of 2 in the acronym aim2 means: undefined

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