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PCNA

  • Proliferating cell nuclear antigen
  • antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer

  • DNA mismatch repair
  • (PCNA), in an orientation-specific manner, such that one face of the donut-shape protein is juxtaposed toward the 3'-OH end at the nick. Loaded PCNA then

  • AOH1996
  • acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for

  • Molecular biology
  • (yellow), a newly-synthesized daughter DNA strand (cyan), three subunits of PCNA (shades of blue), and the catalytic subunit of DNA Polymerase ε (green).

  • DNA polymerase epsilon
  • both PCNA and RFC, and produces mostly ligated DNA products. It is also found that under one condition where DNA polymerase epsilon require PCNA and RFC:

  • P21
  • binding region on PCNA, binding of p21 to this region is proposed to block the binding of processivity factors necessary for PCNA dependent S-phase DNA

  • DNA clamp
  • proliferating cell nuclear antigen (PCNA). The N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated

  • DNA repair
  • cell nuclear antigen (PCNA). Under normal circumstances, PCNA bound to polymerases replicates the DNA. At a site of lesion, PCNA is ubiquitinated, or modified

  • DNA polymerase delta
  • cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor C, through its role as the clamp loader for PCNA (which involves catalysing

  • Ramachandran plot
  • A Ramachandran plot generated from human PCNA, a trimeric DNA clamp protein that contains both β-sheet and α-helix (PDB ID 1AXC). The red, brown, and yellow

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  • CNN
  • CNN

    Commercial News Network

    CNN

  • RAN
  • RAN

    Ratio of Nuclear

    RAN

  • CBO
  • CBO

    Conference of Baltic Oceanographers

    CBO

  • SCWE
  • SCWE

    St Clements Wind Ensemble

    SCWE

  • WPI
  • WPI

    Worldwide Petroleum Index

    WPI

  • JPA
  • JPA

    John Pulsford Associates

    JPA

  • LER
  • LER

    Lunar Electric Rover

    LER

  • RCB
  • RCB

    Richmond City Baseball

    RCB

  • OSEC
  • OSEC

    Office of the Secretary

    OSEC

  • EVH
  • EVH

    Even Voice Harmarnic

    EVH

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