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Muromonab-CD3

Muromonab-CD3 (brand name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant medication given to reduce acute rejection in people with

Transplant rejection

added to immunosuppressive therapy. The monoclonal anti-T cell antibody OKT3, once used to prevent rejection, and still occasionally used to treat severe

Teplizumab

LK, Auger J, Xu D, et al. (June 1998). "Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience". Transplantation Proceedings

Drug-induced aseptic meningitis

antibodies such as infliximab, adalimumab, etanercept, efalizumab, cetuximab, and OKT3 antibodies. Chemotherapeutic drugs such as pemetrexed and cytarabine. Zimelidine

Anti-lymphocyte globulin

term. ALG is more likely to cause side effects than ATG, but is safer than OKT3. The product was manufactured by Upjohn and Merieux, as well as the Schweizerisches

List of therapeutic monoclonal antibodies

pasudotox Lumoxiti mab mouse CD22 Y hairy cell leukemia Muromonab-CD3 Orthoclone OKT3 mab mouse CD3 prevention of organ transplant rejections Nacolomab tafenatox

Monoclonal antibody therapy

monoclonal antibody was a murine IgG2a CD3 specific transplant rejection drug, OKT3 (also called muromonab), in 1986. This drug found use in solid organ transplant

Post-transplant lymphoproliferative disorder

post-transplant lymphoproliferative disorder. Such antibodies include ATG, ALG and OKT3 (muromonab-CD3).[citation needed] Polyclonal PTLD may form tumor masses and

Tse Wen Chang

Nature, 239, 207. Chang TW, Kung PC, Gingras SP, and Goldstein G, 1981, "Does OKT3 monoclonal antibody react with an antigen-recognition structure on human