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BRCT

BRCA1

repeat BRCT domain of the BRCA1 protein is an elongated structure approximately 70 Å long and 30–35 Å wide. The 85–95 amino acid domains in BRCT can be

Bangladesh Rehabilitation Centre for Trauma Victims

Victims (BRCT; Bengali: বিআরসিটি) is a Bangladeshi NGO, working in the area of rehabilitation of trauma victims. It was established in 1992. BRCT began its

BRIP1

a tumor suppressor, by binding to the C terminus between repeats in the BRCT domain. Like the ATPase activity, this interaction depends on phosphorylation

BRCT domain

BRCA1 C Terminus (BRCT) domain is a family of evolutionarily related proteins. It is named after the C-terminal domain of BRCA1, a DNA-repair protein that

TP53BP1

Pavletich NP (Mar 2002). "Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure". Genes & Development. 16 (5): 583–93

TOPBP1

partners through its breast cancer associated gene 1 C-terminus (BRCT) domains. A BRCT domain is structurally defined by a 4 member β sheet that is bookended

BARD1

(residues 46-90), four ankyrin repeats (residues 420-555), and a tandem BRCT domain (residues 568-777). Most, if not all, BRCA1 heterodimerizes with BARD1

Solenoid protein domain

famous example is the case of tandem BRCT domains, found in the tumor suppressor protein BRCA1. While individual BRCT domains are found in certain proteins

Pavletich NP (March 2002). "Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure". Genes & Development. 16 (5): 583–93

DNA polymerase mu

structurally and functionally related to pol λ, and, like pol λ, pol μ has a BRCT domain that is thought to mediate interactions with other DNA repair proteins