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  • P53
  • genes. This domain is followed by the proline rich domain (PXXP), whereby the motif PXXP is repeated (P is a proline and X can be any amino acid). It

  • Protein–protein interaction
  • recognize proline enriched sequences, as polyproline type II helical structure (PXXP motifs)[verification needed] in cell signaling proteins like protein tyrosine

  • DLG4
  • again a protein-protein interaction domain. Its family generally bind to PXXP sites, but in MAGUKs it is known to bind to other sites as well. One of the

  • Small integral membrane protein 14
  • proline residues (9 out of 29; 31%) with several proline-rich sequences (PXXP). Proline-rich domains are usually associated with protein-protein interactions;

  • PTTG1
  • gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities

  • Membrane-associated guanylate kinase
  • again a protein–protein interaction domain. Its family generally bind to PXXP sites, but in MAGUKs it is known to bind to other sites as well. One of the

  • SYNPO2
  • isoforms have been described. Myopodin contains one PPXY motif, multiple PXXP motifs, and two potential nuclear localization sequences (one N-terminal

  • USP8
  • Tanaka N (November 2003). "Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain"

  • GAB2
  • Adjacent to the PH domain is a central, proline-rich domain that contains many PXXP motifs for binding to the SH3 domains of signaling molecules such as Grb2

  • DOK1
  • contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells

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Astrological/horoscope meaning of pxxps. pxxps means: undefined

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    P: Meaning of P in the acronym pxxps means: P has a heavy top standing on just a point to show it's strenght. It means strong, the ability tp perceive weakness and opportunities easily and clear-sightedness. By standing on its own, it shows self-centeredness, a thriving attitude and rigorousness. P also shows disconnection, strong will to go even alone and impartiality.

    X: Meaning of X in the acronym pxxps means: X is a cross bettween two arms of exactly the same lenght. It also balances on two ends at the bottom. It looks like Y with the bottom ends merged in the middle. X is stable, responsible, gorgeous, and spiritual as it opens upwards. X also shows enlightenment as it seeks to explore by extending its arms.

    S: Meaning of S in the acronym pxxps means: S is a single strand that goes forward and backwards. It shows a willingness to explore. Friendliness, perceptiveness and accommodating are all S qualities. The ends pointing forward and backwards shows a conflicting nature with itself and a degree of puzzlement.

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